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Gene: Bmpr2 (bone morphogenetic protein receptor type 2) Rattus norvegicus
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Symbol: Bmpr2
Name: bone morphogenetic protein receptor type 2
Description: Exhibits growth factor binding activity. Involved in brain development and retina development in camera-type eye. Localizes to several cellular components, including apical plasma membrane; basal plasma membrane; and caveola. Human ortholog(s) of this gene implicated in heart septal defect; primary pulmonary hypertension; pulmonary hypertension; and pulmonary venoocclusive disease. Orthologous to human BMPR2 (bone morphogenetic protein receptor type 2); PARTICIPATES IN Bone morphogenetic proteins signaling pathway; cytokine mediated signaling pathway; transforming growth factor-beta superfamily mediated signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Bmpr-II; bone morphogenetic protein receptor type II; bone morphogenetic protein receptor type II (serine/threonine kinase); bone morphogenetic protein receptor type-2; bone morphogenetic protein receptor, type II (serine/threonine kinase); bone morphogenic protein receptor, type II (serine/threonine kinase)
Orthologs:
Homo sapiens (human) : BMPR2 (bone morphogenetic protein receptor type 2)  HGNC  Alliance
Mus musculus (house mouse) : Bmpr2 (bone morphogenetic protein receptor, type II (serine/threonine kinase))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bmpr2 (bone morphogenetic protein receptor type 2)
Pan paniscus (bonobo/pygmy chimpanzee) : BMPR2 (bone morphogenetic protein receptor type 2)
Canis lupus familiaris (dog) : BMPR2 (bone morphogenetic protein receptor type 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bmpr2 (bone morphogenetic protein receptor type 2)
Sus scrofa (pig) : BMPR2 (bone morphogenetic protein receptor type 2)
Chlorocebus sabaeus (African green monkey) : BMPR2 (bone morphogenetic protein receptor type 2)
Heterocephalus glaber (naked mole-rat) : Bmpr2 (bone morphogenetic protein receptor type 2)
more info ...
Allele / Splice: Bmpr2em1Sage   Bmpr2em2Sage  
Genetic Models: F344-Bmpr2em2Sage+/- F344-Bmpr2em1Sage+/-
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0966,568,074 - 66,683,019 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl966,568,074 - 66,676,494 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0966,371,542 - 66,486,121 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4958,327,587 - 58,436,057 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1958,524,438 - 58,554,549 (+)NCBI
Celera958,627,253 - 58,735,336 (+)NCBICelera
Cytogenetic Map9q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Bmpr2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 71082
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2020-05-19
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.