Gene: Dnm1 (dynamin 1) Rattus norvegicus
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Symbol: Dnm1
Name: dynamin 1
Description: Exhibits several functions, including D2 dopamine receptor binding activity, SH3 domain binding activity, and identical protein binding activity; involved in G protein-coupled receptor internalization, positive regulation of synaptic vesicle endocytosis, and response to amyloid-beta; localizes to several cellular components, including the cytoplasm, presynaptic endocytic zone membrane, and protein-containing complex; biomarker of Alzheimer's disease; orthologous to human DNM1 (dynamin 1); PARTICIPATES IN clathrin-dependent synaptic vesicle endocytosis; eicosanoid signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 3,3',4,4',5-pentachlorobiphenyl; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: B-dynamin; D100; Dnm; dynamin, brain; dynamin-1
Orthologs:
Homo sapiens (human) : DNM1 (dynamin 1)  HGNC  Alliance
Mus musculus (house mouse) : Dnm1 (dynamin 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dnm1 (dynamin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DNM1 (dynamin 1)
Canis lupus familiaris (dog) : DNM1 (dynamin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dnm1 (dynamin 1)
Sus scrofa (pig) : DNM1 (dynamin 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0311,338,081 - 11,382,043 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0316,686,951 - 16,730,913 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4311,434,778 - 11,478,452 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1311,331,147 - 11,374,785 (-)NCBI
Celera310,349,401 - 10,391,382 (-)NCBICelera
Cytogenetic Map3p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Dnm1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 71096
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.