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Gene: Kiss1 (KiSS-1 metastasis-suppressor) Rattus norvegicus
Symbol: Kiss1
Name: KiSS-1 metastasis-suppressor
Description: Exhibits kisspeptin receptor binding activity. Involved in several processes, including generation of ovulation cycle rhythm; positive regulation of cell communication; and positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway. Localizes to several cellular components, including apical plasma membrane; extracellular space; and neuronal cell body. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 13 with or without anosmia. Orthologous to human KISS1 (KiSS-1 metastasis suppressor); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 17beta-estradiol 3-benzoate.
Type: protein-coding
Also known as: eseptin; Kiss1 variant E1a-E2b-E3; Kiss1 variant E1b-E2a-E3; Kiss1 variant E1b-E2b-E3; kisspeptin-1; metastasis-suppressor; metastasis-suppressor KiSS-1; metastin; MLL septin-like fusion; MLL septin-like fusion gene
Homo sapiens (human) : KISS1 (KiSS-1 metastasis suppressor)  HGNC  Alliance
Mus musculus (house mouse) : Kiss1 (KiSS-1 metastasis-suppressor)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kiss1 (KiSS-1 metastasis suppressor)
Pan paniscus (bonobo/pygmy chimpanzee) : KISS1 (KiSS-1 metastasis suppressor)
Canis lupus familiaris (dog) : KISS1 (KiSS-1 metastasis suppressor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kiss1 (KiSS-1 metastasis suppressor)
Sus scrofa (pig) : KISS1 (KiSS-1 metastasis suppressor)
Chlorocebus sabaeus (African green monkey) : KISS1 (KiSS-1 metastasis suppressor)
Heterocephalus glaber (naked mole-rat) : Kiss1 (KiSS-1 metastasis suppressor)
more info ...
Is Marker For: Strains:   WI-Kiss1tm1Nips  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01350,529,506 - 50,537,603 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1350,529,510 - 50,535,389 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01355,582,365 - 55,590,432 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41346,244,786 - 46,247,288 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11346,258,828 - 46,261,331 (+)NCBI
Celera1345,110,972 - 45,113,474 (+)NCBICelera
Cytogenetic Map13q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Kiss1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 727850
Created: 2003-11-05
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.