Gene: Gsdme (gasdermin E) Rattus norvegicus
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Symbol: Gsdme
Name: gasdermin E
Description: Predicted to have cardiolipin binding activity and phosphatidylinositol-4,5-bisphosphate binding activity; predicted to be involved in several processes, including cellular response to tumor necrosis factor, cellular response to virus, and positive regulation of signal transduction; predicted to localize to the cytosol and plasma membrane; orthologous to human GSDME (gasdermin E); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; copper atom.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: deafness, autosomal dominant 5; deafness, autosomal dominant 5 (human); deafness, autosomal dominant 5 homolog; deafness, autosomal dominant 5 homolog (human); Dfna5; DFNA5, deafness associated tumor suppressor; Dfna5h; non-syndromic hearing impairment protein 5
Orthologs:
Homo sapiens (human) : GSDME (gasdermin E)  HGNC  Alliance
Mus musculus (house mouse) : Gsdme (gasdermin E)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gsdme (gasdermin E)
Pan paniscus (bonobo/pygmy chimpanzee) : GSDME (gasdermin E)
Canis lupus familiaris (dog) : GSDME (gasdermin E)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gsdme (gasdermin E)
Sus scrofa (pig) : GSDME (gasdermin E)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0479,934,075 - 79,999,678 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04144,606,016 - 144,670,696 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4478,431,841 - 78,492,217 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1478,707,973 - 78,721,124 (-)NCBI
Celera474,170,353 - 74,229,548 (-)NCBICelera
Cytogenetic Map4q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Gsdme
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 727871
Created: 2003-11-05
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.