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Gene: Corin (corin, serine peptidase) Rattus norvegicus
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Symbol: Corin
Name: corin, serine peptidase
Description: Predicted to have serine-type endopeptidase activity. Involved in regulation of blood pressure and regulation of renal sodium excretion. Localizes to the cytoplasmic vesicle and integral component of plasma membrane. Biomarker of congestive heart failure. Human ortholog(s) of this gene implicated in hypertension and pre-eclampsia. Orthologous to human CORIN (corin, serine peptidase); PARTICIPATES IN atrial natriuretic peptide signaling pathway; INTERACTS WITH 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine; 3,7-dihydropurine-6-thione; aflatoxin B1.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: atrial natriuretic peptide-converting enzyme; LOC289596; pro-ANP-converting enzyme
Orthologs:
Homo sapiens (human) : CORIN (corin, serine peptidase)  HGNC  Alliance
Mus musculus (house mouse) : Corin (corin, serine peptidase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Corin (corin, serine peptidase)
Pan paniscus (bonobo/pygmy chimpanzee) : CORIN (corin, serine peptidase)
Canis lupus familiaris (dog) : CORIN (corin, serine peptidase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Corin (corin, serine peptidase)
Sus scrofa (pig) : CORIN (corin, serine peptidase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01438,247,379 - 38,474,931 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01438,103,553 - 38,135,786 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01438,163,662 - 38,284,564 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01438,058,862 - 38,064,976 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41438,109,932 - 38,339,631 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11438,113,281 - 38,342,022 (+)NCBI
Celera1434,932,916 - 35,141,793 (+)NCBICelera
Cytogenetic Map14p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Corin
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 727887
Created: 2003-11-05
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.