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Gene: Pde4c (phosphodiesterase 4C) Rattus norvegicus
Symbol: Pde4c
Name: phosphodiesterase 4C
Description: Predicted to have 3',5'-cyclic-AMP phosphodiesterase activity. Involved in negative regulation of insulin secretion involved in cellular response to glucose stimulus. Predicted to localize to the cilium. Orthologous to human PDE4C (phosphodiesterase 4C); PARTICIPATES IN protein kinase A (PKA) signaling pathway; purine metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cAMP-specific 3',5'-cyclic phosphodiesterase 4C; cAMP-specific 3,5-cyclic phosphodiesterase 4C; cAMP-specific 35-cyclic phosphodiesterase 4C; Dpde1; MGC188426; phosphodiesterase 4C, cAMP specific; phosphodiesterase 4C, cAMP-specific; phosphodiesterase 4C, cAMP-specific (phosphodiesterase E1 dunce homolog, Drosophila)
Homo sapiens (human) : PDE4C (phosphodiesterase 4C)  HGNC  Alliance
Mus musculus (house mouse) : Pde4c (phosphodiesterase 4C, cAMP specific)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pde4c (phosphodiesterase 4C)
Pan paniscus (bonobo/pygmy chimpanzee) : PDE4C (phosphodiesterase 4C)
Canis lupus familiaris (dog) : PDE4C (phosphodiesterase 4C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pde4c (phosphodiesterase 4C)
Sus scrofa (pig) : PDE4C (phosphodiesterase 4C)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01620,442,305 - 20,466,386 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01620,298,910 - 20,318,430 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41619,197,277 - 19,215,627 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11619,197,497 - 19,200,188 (-)NCBI
Celera1618,883,915 - 18,902,144 (-)NCBICelera
Celera1618,903,793 - 18,907,574 (-)NCBICelera
Cytogenetic Map16p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Pde4c
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 727918
Created: 2003-11-05
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.