Gene: Spg7 (SPG7 matrix AAA peptidase subunit, paraplegin) Rattus norvegicus
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Symbol: Spg7
Name: SPG7 matrix AAA peptidase subunit, paraplegin
Description: Predicted to have metalloendopeptidase activity; involved in mitochondrial outer membrane permeabilization involved in programmed cell death; predicted to localize to the m-AAA complex and mitochondrial permeability transition pore complex; orthologous to human SPG7 (SPG7 matrix AAA peptidase subunit, paraplegin); INTERACTS WITH 2,4,6-trinitrotoluene; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: paraplegin; spastic paraplegia 7 homolog; spastic paraplegia 7 homolog (human); SPG7, paraplegin matrix AAA peptidase subunit
Orthologs:
Homo sapiens (human) : SPG7 (SPG7 matrix AAA peptidase subunit, paraplegin)  HGNC  Alliance
Mus musculus (house mouse) : Spg7 (SPG7, paraplegin matrix AAA peptidase subunit)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Spg7 (SPG7 matrix AAA peptidase subunit, paraplegin)
Pan paniscus (bonobo/pygmy chimpanzee) : SPG7 (SPG7 matrix AAA peptidase subunit, paraplegin)
Canis lupus familiaris (dog) : SPG7 (SPG7 matrix AAA peptidase subunit, paraplegin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Spg7 (SPG7 matrix AAA peptidase subunit, paraplegin)
Sus scrofa (pig) : SPG7 (SPG7 matrix AAA peptidase subunit, paraplegin)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01955,880,549 - 55,914,729 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01966,586,319 - 66,618,933 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41953,400,904 - 53,433,742 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11953,405,784 - 53,438,623 (+)NCBI
Celera1950,353,488 - 50,385,526 (+)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Spg7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 727940
Created: 2003-11-05
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.