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Gene: NPY (neuropeptide Y) Homo sapiens
Symbol: NPY
Name: neuropeptide Y
Description: Predicted to have neuropeptide Y receptor binding activity and neuropeptide hormone activity. Involved in several processes, including defense response to other organism; nervous system development; and response to yeast. Localizes to the Golgi apparatus. Implicated in several diseases, including Huntington's disease; alcohol use disorder; artery disease (multiple); epilepsy (multiple); and type 2 diabetes mellitus. Biomarker of Alzheimer's disease; dementia; and peripheral artery disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: prepro-neuropeptide Y; pro-neuropeptide Y; PYY4
Mus musculus (house mouse) : Npy (neuropeptide Y)  MGI  Alliance
Rattus norvegicus (Norway rat) : Npy (neuropeptide Y)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Npy (neuropeptide Y)
Pan paniscus (bonobo/pygmy chimpanzee) : NPY (neuropeptide Y)
Canis lupus familiaris (dog) : NPY (neuropeptide Y)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Npy (neuropeptide Y)
Sus scrofa (pig) : NPY (neuropeptide Y)
Chlorocebus sabaeus (green monkey) : NPY (neuropeptide Y)
Heterocephalus glaber (naked mole-rat) : Npy (neuropeptide Y)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl724,284,188 - 24,291,862 (+)Ensembl
GRCh38724,284,190 - 24,291,862 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37724,323,807 - 24,331,484 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36724,290,334 - 24,298,002 (+)NCBINCBI36hg18NCBI36
Build 34724,097,048 - 24,104,717NCBI
Celera724,312,617 - 24,320,302 (+)NCBI
Cytogenetic Map7p15.3NCBI
HuRef724,208,802 - 24,216,490 (+)NCBIHuRef
CHM1_1724,325,406 - 24,333,092 (+)NCBICHM1_1
CRA_TCAGchr7v2724,375,683 - 24,383,371 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on NPY
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 730830
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2020-01-14
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.