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Gene: CHGA (chromogranin A) Homo sapiens
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Symbol: CHGA
Name: chromogranin A
Description: Involved in several processes, including defense response to bacterium; mast cell chemotaxis; and mast cell cytokine production. Localizes to the perinuclear region of cytoplasm. Implicated in IgA glomerulonephritis; end stage renal failure; hypertension; and prostate cancer. Biomarker of end stage renal failure and pheochromocytoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: betagranin (N-terminal fragment of chromogranin A); catestatin; CGA; chromofungin; chromogranin-A; parathyroid secretory protein 1; pituitary secretory protein I; SP-I
Orthologs:
Mus musculus (house mouse) : Chga (chromogranin A)  MGI  Alliance
Rattus norvegicus (Norway rat) : Chga (chromogranin A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Chga (chromogranin A)
Pan paniscus (bonobo/pygmy chimpanzee) : CHGA (chromogranin A)
Canis lupus familiaris (dog) : CHGA (uncharacterized CHGA)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Chga (chromogranin A)
Sus scrofa (pig) : CHGA (chromogranin A)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381492,922,594 - 92,935,293 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371493,389,445 - 93,401,638 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361492,459,198 - 92,471,391 (+)NCBINCBI36hg18NCBI36
Build 341492,459,244 - 92,471,389NCBI
Celera1473,443,584 - 73,455,777 (+)NCBI
Cytogenetic Map14q32.12NCBI
HuRef1473,571,127 - 73,583,341 (+)NCBIHuRef
CHM1_11493,327,694 - 93,339,887 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CHGA
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 730836
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2019-11-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.