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Gene: Rgs5 (regulator of G-protein signaling 5) Mus musculus
Symbol: Rgs5
Name: regulator of G-protein signaling 5
Description: Predicted to have GTPase activator activity. Predicted to be involved in negative regulation of vascular smooth muscle cell proliferation and signal transduction. Predicted to localize to the cytoplasm and membrane. Human ortholog(s) of this gene implicated in essential hypertension. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and visual system. Orthologous to human RGS5 (regulator of G protein signaling 5); PARTICIPATES IN calcium signaling pathway via the calcium-sensing receptor; G protein mediated signaling pathway via Galphai family; G protein mediated signaling pathway via Galphaq family; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1110070A02Rik
Homo sapiens (human) : RGS5 (regulator of G protein signaling 5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rgs5 (regulator of G-protein signaling 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rgs5 (regulator of G protein signaling 5)
Pan paniscus (bonobo/pygmy chimpanzee) : RGS5 (regulator of G protein signaling 5)
Canis lupus familiaris (dog) : RGS5 (regulator of G protein signaling 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rgs5 (regulator of G protein signaling 5)
Sus scrofa (pig) : RGS5 (regulator of G protein signaling 5)
Chlorocebus sabaeus (African green monkey) : RGS5 (regulator of G protein signaling 5)
Heterocephalus glaber (naked mole-rat) : Rgs5 (regulator of G protein signaling 5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1169,655,501 - 169,695,813 (+)EnsemblGRCm38mm10GRCm38
GRCm381169,655,501 - 169,695,813 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371171,585,632 - 171,623,657 (+)NCBIGRCm37mm9NCBIm37
MGSCv361171,492,176 - 171,530,201 (+)NCBImm8
Celera1172,079,009 - 172,116,960 (+)NCBICelera
Cytogenetic Map1H2.3NCBI
cM Map176.84NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Rgs5
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 730867
Created: 2003-12-10
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.