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Gene: PRKAA2 (protein kinase AMP-activated catalytic subunit alpha 2) Homo sapiens
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Symbol: PRKAA2
Name: protein kinase AMP-activated catalytic subunit alpha 2
Description: Exhibits AMP-activated protein kinase activity and protein serine/threonine/tyrosine kinase activity. Predicted to be involved in several processes, including energy homeostasis; regulation of cellular catabolic process; and regulation of protein modification process. Localizes to the Golgi apparatus and nuclear speck. Implicated in type 2 diabetes mellitus.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5'-AMP-activated protein kinase catalytic subunit alpha-2; 5'-AMP-activated protein kinase, catalytic alpha-2 chain; ACACA kinase; acetyl-CoA carboxylase kinase; AMP-activated protein kinase alpha-2 subunit variant 2; AMP-activated protein kinase alpha-2 subunit variant 3; AMPK; AMPK alpha 2; AMPK subunit alpha-2; AMPK-alpha-2 chain; AMPK2; AMPKa2; HMGCR kinase; hydroxymethylglutaryl-CoA reductase kinase; PRKAA
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38156,645,314 - 56,715,335 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37157,110,990 - 57,181,008 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36156,883,578 - 56,953,596 (+)NCBINCBI36hg18NCBI36
Build 34156,823,040 - 56,886,142NCBI
Celera155,395,857 - 55,465,885 (+)NCBI
Cytogenetic Map1p32.2NCBI
HuRef155,223,513 - 55,293,426 (+)NCBIHuRef
CHM1_1157,226,353 - 57,296,384 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


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References - curated
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Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on PRKAA2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 730888
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.