Gene: IL18 (interleukin 18) Homo sapiens
Analyze
Symbol: IL18
Name: interleukin 18
Description: The protein encoded by this gene is a proinflammatory cytokine that augments natural killer cell activity in spleen cells, and stimulates interferon gamma production in T-helper type I cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2011]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: iboctadekin; IFN-gamma-inducing factor; IGIF; IL-1 gamma; IL-18; IL-1g; IL1F4; interferon gamma-inducing factor; interleukin 18 (interferon-gamma-inducing factor); interleukin-1 gamma; interleukin-18; MGC12320
Orthologs:
Mus musculus (house mouse) : Il18 (interleukin 18)  MGI  Alliance
Rattus norvegicus (Norway rat) : Il18 (interleukin 18)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il18 (interleukin 18)
Pan paniscus (bonobo/pygmy chimpanzee) : IL18 (interleukin 18)
Canis lupus familiaris (dog) : IL18 (interleukin 18)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il18 (interleukin 18)
Sus scrofa (pig) : IL18 (interleukin 18)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811112,143,251 - 112,164,117 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711112,013,974 - 112,034,840 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611111,519,186 - 111,540,050 (-)NCBINCBI36hg18NCBI36
Build 3411111,519,185 - 111,540,050NCBI
Celera11109,167,214 - 109,188,073 (-)NCBI
Cytogenetic Map11q23.1NCBI
HuRef11107,938,095 - 107,959,011 (-)NCBIHuRef
CHM1_111111,897,441 - 111,918,303 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on IL18
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 730894
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2019-06-04
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.