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Gene: EREG (epiregulin) Homo sapiens
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Symbol: EREG
Name: epiregulin
Description: Predicted to have epidermal growth factor receptor binding activity and growth factor activity. Involved in several processes, including keratinocyte proliferation; mRNA transcription; and positive regulation of macromolecule metabolic process. Localizes to extracellular space.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Ep; EPR; ER; proepiregulin
Orthologs:
Mus musculus (house mouse) : Ereg (epiregulin)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ereg (epiregulin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ereg (epiregulin)
Pan paniscus (bonobo/pygmy chimpanzee) : EREG (epiregulin)
Canis lupus familiaris (dog) : EREG (epiregulin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ereg (epiregulin)
Sus scrofa (pig) : EREG (epiregulin)
Chlorocebus sabaeus (African green monkey) : EREG (epiregulin)
Heterocephalus glaber (naked mole-rat) : Ereg (epiregulin)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl474,365,145 - 74,388,749 (+)EnsemblGRCh38hg38GRCh38
GRCh38474,365,145 - 74,388,749 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37475,230,860 - 75,254,477 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36475,449,724 - 75,473,341 (+)NCBINCBI36hg18NCBI36
Build 34475,595,894 - 75,619,512NCBI
Celera472,591,116 - 72,614,730 (+)NCBI
Cytogenetic Map4q13.3NCBI
HuRef471,041,824 - 71,065,447 (+)NCBIHuRef
CHM1_1475,266,712 - 75,290,347 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on EREG
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 730898
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2020-05-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.