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Gene: HMOX1 (heme oxygenase 1) Homo sapiens
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Symbol: HMOX1
Name: heme oxygenase 1
Description: Exhibits heme binding activity; heme oxygenase (decyclizing) activity; and protein homodimerization activity. Involved in several processes, including porphyrin-containing compound catabolic process; positive regulation of sprouting angiogenesis; and regulation of smooth muscle cell proliferation. Localizes to the endoplasmic reticulum and perinuclear region of cytoplasm. Implicated in several diseases, including artery disease (multiple); cerebrovascular disease (multiple); factor VIII deficiency; lung disease (multiple); and type 2 diabetes mellitus. Biomarker of several diseases, including Behcet's disease; Henoch-Schoenlein purpura; cystic fibrosis; lung disease (multiple); and obstructive sleep apnea.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: bK286B10; heat shock protein, 32-kD; heme oxygenase (decycling) 1; HMOX1D; HO-1; HSP32
Orthologs:
Mus musculus (house mouse) : Hmox1 (heme oxygenase 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Hmox1 (heme oxygenase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hmox1 (heme oxygenase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : HMOX1 (heme oxygenase 1)
Canis lupus familiaris (dog) : HMOX1 (heme oxygenase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hmox1 (heme oxygenase 1)
Sus scrofa (pig) : HMOX1 (heme oxygenase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382235,381,096 - 35,394,207 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372235,777,060 - 35,790,207 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362234,107,087 - 34,120,194 (+)NCBINCBI36hg18NCBI36
Build 342234,101,640 - 34,114,748NCBI
Celera2219,579,740 - 19,592,881 (+)NCBI
Cytogenetic Map22q12.3NCBI
HuRef2218,737,577 - 18,750,716 (+)NCBIHuRef
CHM1_12235,735,791 - 35,748,937 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model