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Gene: CCND2 (cyclin D2) Homo sapiens
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Symbol: CCND2
Name: cyclin D2
Description: Exhibits protein kinase binding activity. Predicted to contribute to protein kinase activity. Involved in negative regulation of apoptotic process; positive regulation of cell cycle; and positive regulation of cell population proliferation. Localizes to several cellular components, including the chromatin; cyclin-dependent protein kinase holoenzyme complex; and nucleus. Implicated in ductal carcinoma in situ; invasive lobular carcinoma; prostate cancer; and transitional cell carcinoma. Biomarker of germinoma; granulosa cell tumor; multiple myeloma; nephroblastoma; and seminoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: G1/S-specific cyclin D2; G1/S-specific cyclin-D2; KIAK0002; MGC102758; MPPH3
Orthologs:
Mus musculus (house mouse) : Ccnd2 (cyclin D2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ccnd2 (cyclin D2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ccnd2 (cyclin D2)
Pan paniscus (bonobo/pygmy chimpanzee) : CCND2 (cyclin D2)
Canis lupus familiaris (dog) : CCND2 (cyclin D2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ccnd2 (cyclin D2)
Sus scrofa (pig) : CCND2 (cyclin D2)
more info ...
Related Pseudogenes: CCND2P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38124,273,762 - 4,305,353 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37124,382,901 - 4,414,522 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36124,253,199 - 4,284,777 (+)NCBINCBI36hg18NCBI36
Build 34124,253,198 - 4,284,777NCBI
Celera126,004,961 - 6,036,590 (+)NCBI
Cytogenetic Map12p13.32NCBI
HuRef124,239,192 - 4,271,184 (+)NCBIHuRef
CHM1_1124,382,561 - 4,414,148 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on CCND2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 730903
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.