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Gene: Sema3a (sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A) Mus musculus
Symbol: Sema3a
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
Description: Exhibits chemorepellent activity; neuropilin binding activity; and semaphorin receptor binding activity. Involved in several processes, including dichotomous subdivision of terminal units involved in salivary gland branching; nervous system development; and ventral trunk neural crest cell migration. Localizes to extracellular space. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 16 with or without anosmia. Is expressed in several structures, including alimentary system; central nervous system; metanephros; respiratory system; and sensory organ. Orthologous to human SEMA3A (semaphorin 3A); INTERACTS WITH 1,2-dichloroethane; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: coll-1; collapsin-1; Hsema-I; sema D; sema III; SEMA1; Semad; semaphorin III; semaphorin-3A; semaphorin-D; SemD
Homo sapiens (human) : SEMA3A (semaphorin 3A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sema3a (semaphorin 3A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sema3a (semaphorin 3A)
Pan paniscus (bonobo/pygmy chimpanzee) : SEMA3A (semaphorin 3A)
Canis lupus familiaris (dog) : SEMA3A (semaphorin 3A)
Sus scrofa (pig) : SEMA3A (semaphorin 3A)
Chlorocebus sabaeus (African green monkey) : SEMA3A (semaphorin 3A)
Heterocephalus glaber (naked mole-rat) : Sema3a (semaphorin 3A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl513,125,414 - 13,602,565 (+)EnsemblGRCm38mm10GRCm38
GRCm38513,124,822 - 13,603,485 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37513,399,309 - 13,602,571 (+)NCBIGRCm37mm9NCBIm37
MGSCv36513,405,315 - 13,608,571 (+)NCBImm8
Celera1223,770,632 - 23,979,473 (+)NCBICelera
Cytogenetic Map5A1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Sema3a
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 730922
Created: 2003-12-10
Species: Mus musculus
Last Modified: 2020-05-19
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.