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Gene: Glra1 (glycine receptor, alpha 1 subunit) Mus musculus
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Symbol: Glra1
Name: glycine receptor, alpha 1 subunit
Description: Exhibits extracellularly glycine-gated chloride channel activity; glycine binding activity; and transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to chloride channel activity. Involved in several processes, including adult walking behavior; chemical synaptic transmission; and regulation of respiratory gaseous exchange by nervous system process. Localizes to several cellular components, including external side of plasma membrane; glycinergic synapse; and inhibitory synapse. Used to study hyperekplexia 1. Human ortholog(s) of this gene implicated in hyperekplexia 1. Is expressed in brain and spinal cord. Orthologous to human GLRA1 (glycine receptor alpha 1); PARTICIPATES IN Inhibitory synaptic transmission pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; genistein.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: B230397M16Rik; glycine receptor 48 kDa subunit; glycine receptor strychnine-binding subunit; glycine receptor subunit alpha-1; nmf11; oscillator; ot; spasmodic; spd
Orthologs:
Homo sapiens (human) : GLRA1 (glycine receptor alpha 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Glra1 (glycine receptor, alpha 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Glra1 (glycine receptor alpha 1)
Pan paniscus (bonobo/pygmy chimpanzee) : GLRA1 (glycine receptor alpha 1)
Canis lupus familiaris (dog) : GLRA1 (glycine receptor alpha 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Glra1 (glycine receptor alpha 1)
Sus scrofa (pig) : GLRA1 (glycine receptor alpha 1)
Chlorocebus sabaeus (African green monkey) : GLRA1 (glycine receptor alpha 1)
Heterocephalus glaber (naked mole-rat) : Glra1 (glycine receptor alpha 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1155,514,238 - 55,608,198 (-)EnsemblGRCm38mm10GRCm38
GRCm381155,514,239 - 55,608,198 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371155,328,315 - 55,421,292 (-)NCBIGRCm37mm9NCBIm37
MGSCv361155,358,236 - 55,451,213 (-)NCBImm8
Celera1160,300,816 - 60,360,053 (-)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1133.12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
 
More on Glra1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 730940
Created: 2003-12-10
Species: Mus musculus
Last Modified: 2020-05-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.