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Gene: Abcb11 (ATP-binding cassette, sub-family B (MDR/TAP), member 11) Mus musculus
Symbol: Abcb11
Name: ATP-binding cassette, sub-family B (MDR/TAP), member 11
Description: Predicted to have ATPase-coupled transmembrane transporter activity; canalicular bile acid transmembrane transporter activity; and carbohydrate transmembrane transporter activity. Predicted to be involved in canalicular bile acid transport; drug export; and transmembrane transport. Localizes to the apical part of cell; intercellular canaliculus; and membrane. Human ortholog(s) of this gene implicated in benign recurrent intrahepatic cholestasis 2; intrahepatic cholestasis; liver cirrhosis; and progressive familial intrahepatic cholestasis 2. Is expressed in liver. Orthologous to human ABCB11 (ATP binding cassette subfamily B member 11).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ABC16; ATP-binding cassette sub-family B member 11; ATP-binding cassette, sub-family B, member 11; bile salt export pump; Bsep; Lith1; PFIC2; PGY4; sister of P-glycoprotein; SPGP
Homo sapiens (human) : ABCB11 (ATP binding cassette subfamily B member 11)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Abcb11 (ATP binding cassette subfamily B member 11)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Abcb11 (ATP binding cassette subfamily B member 11)
Pan paniscus (bonobo/pygmy chimpanzee) : ABCB11 (ATP binding cassette subfamily B member 11)
Canis lupus familiaris (dog) : ABCB11 (ATP binding cassette subfamily B member 11)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Abcb11 (ATP binding cassette subfamily B member 11)
Sus scrofa (pig) : ABCB11 (ATP binding cassette subfamily B member 11)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl269,238,282 - 69,342,616 (-)Ensembl
GRCm38269,238,282 - 69,342,616 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37269,076,339 - 69,180,673 (-)NCBIGRCm37mm9NCBIm37
MGSCv36269,039,121 - 69,143,426 (-)NCBImm8
Celera270,904,503 - 71,008,403 (-)NCBICelera
Cytogenetic Map2 C2NCBI
cM Map239.69NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Abcb11
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 730945
Created: 2003-12-10
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.