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Gene: NOS2 (nitric oxide synthase 2) Homo sapiens
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Symbol: NOS2
Name: nitric oxide synthase 2
Description: Exhibits nitric-oxide synthase activity. Involved in several processes, including cytokine secretion; nitric oxide biosynthetic process; and prostaglandin secretion. Localizes to the cytosol and peroxisome. Implicated in several diseases, including dementia (multiple); hypertension (multiple); malaria; pulmonary tuberculosis; and type 2 diabetes mellitus. Biomarker of several diseases, including artery disease (multiple); cystic fibrosis; lung disease (multiple); obesity; and obstructive sleep apnea.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: HEP-NOS; hepatocyte NOS; inducible NO synthase; inducible NOS; INOS; nitric oxide synthase 2, inducible; nitric oxide synthase 2A (inducible, hepatocytes); nitric oxide synthase, inducible; nitric oxide synthase, macrophage; NOS; NOS type II; NOS, type II; NOS2A; peptidyl-cysteine S-nitrosylase NOS2
Orthologs:
Mus musculus (house mouse) : Nos2 (nitric oxide synthase 2, inducible)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nos2 (nitric oxide synthase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nos2 (nitric oxide synthase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : NOS2 (nitric oxide synthase 2)
Canis lupus familiaris (dog) : NOS2 (nitric oxide synthase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nos2 (nitric oxide synthase 2)
Sus scrofa (pig) : NOS2 (nitric oxide synthase 2)
more info ...
Related Pseudogenes: NOS2P1   NOS2P2   NOS2P3   NOS2P4  
Allele / Splice: See ClinVar data
Is Marker For: QTLs:   BP16_H  
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381727,756,766 - 27,800,529 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371726,083,792 - 26,127,555 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361723,107,919 - 23,151,682 (-)NCBINCBI36hg18NCBI36
Build 341723,107,919 - 23,151,682NCBI
Celera1722,945,649 - 22,989,408 (-)NCBI
Cytogenetic Map17q11.2NCBI
HuRef1722,290,738 - 22,334,499 (-)NCBIHuRef
CHM1_11726,146,509 - 26,190,263 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model