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Gene: Tgfb2 (transforming growth factor, beta 2) Mus musculus
Symbol: Tgfb2
Name: transforming growth factor, beta 2
Description: Predicted to have several functions, including amyloid-beta binding activity; protein dimerization activity; and transforming growth factor beta receptor binding activity. Involved in several processes, including animal organ development; regulation of heart morphogenesis; and tube morphogenesis. Localizes to several cellular components, including the axon; endosome; and neuronal cell body. Used to study Loeys-Dietz syndrome. Human ortholog(s) of this gene implicated in Loeys-Dietz syndrome 4 and colorectal cancer. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and sensory organ. Orthologous to human TGFB2 (transforming growth factor beta 2).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BB105277; TGF-beta-2; Tgf-beta2; Tgfb-2; transforming growth factor beta-2; transforming growth factor beta-2 proprotein
Homo sapiens (human) : TGFB2 (transforming growth factor beta 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tgfb2 (transforming growth factor, beta 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tgfb2 (transforming growth factor beta 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TGFB2 (transforming growth factor beta 2)
Canis lupus familiaris (dog) : TGFB2 (transforming growth factor beta 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tgfb2 (transforming growth factor beta 2)
Sus scrofa (pig) : TGFB2 (transforming growth factor beta 2)
Chlorocebus sabaeus (green monkey) : TGFB2 (transforming growth factor beta 2)
Heterocephalus glaber (naked mole-rat) : Tgfb2 (transforming growth factor beta 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1186,622,792 - 186,705,989 (-)Ensembl
GRCm381186,622,787 - 186,709,697 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371188,447,065 - 188,529,871 (-)NCBIGRCm37mm9NCBIm37
MGSCv361188,324,430 - 188,406,777 (-)NCBImm8
Celera1193,563,609 - 193,649,724 (-)NCBICelera
Cytogenetic Map1 H5NCBI
cM Map189.95NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Tgfb2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 730954
Created: 2003-12-10
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.