Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: GRM5 (glutamate metabotropic receptor 5) Homo sapiens
Analyze
Symbol: GRM5
Name: glutamate metabotropic receptor 5
Description: Exhibits G protein-coupled receptor activity; glutamate receptor activity; and identical protein binding activity. Involved in several processes, including calcium-mediated signaling using intracellular calcium source; cellular response to amyloid-beta; and regulation of cellular protein metabolic process. Localizes to the integral component of plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: glutamate receptor, metabotropic 5; GPRC1E; GRM5 variant 9; metabotropic glutamate receptor 5; metabotropic glutamate receptor 5 variant F; metabotropic glutamate receptor 5 variant G; metabotropic glutamate receptor 5 variant H; mGlu5; MGLUR5; PPP1R86
Orthologs:
Mus musculus (house mouse) : Grm5 (glutamate receptor, metabotropic 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Grm5 (glutamate metabotropic receptor 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Grm5 (glutamate metabotropic receptor 5)
Pan paniscus (bonobo/pygmy chimpanzee) : GRM5 (glutamate metabotropic receptor 5)
Canis lupus familiaris (dog) : GRM5 (glutamate metabotropic receptor 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Grm5 (glutamate metabotropic receptor 5)
Sus scrofa (pig) : GRM5 (glutamate metabotropic receptor 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381188,504,576 - 89,065,963 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371188,237,256 - 88,796,846 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361187,880,626 - 88,420,838 (-)NCBINCBI36hg18NCBI36
Build 341187,880,625 - 88,420,838NCBI
Celera1185,835,181 - 86,394,276 (+)NCBI
Cytogenetic Map11q14.2-q14.3NCBI
HuRef1184,476,702 - 85,036,122 (-)NCBIHuRef
CHM1_11188,120,759 - 88,679,848 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on GRM5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 730960
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.