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Gene: CDC42 (cell division cycle 42) Homo sapiens
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Symbol: CDC42
Name: cell division cycle 42
Description: Exhibits several functions, including GBD domain binding activity; GTP binding activity; and enzyme binding activity. Involved in several processes, including cell surface receptor signaling pathway; positive regulation of cellular component organization; and regulation of cell cycle process. Localizes to several cellular components, including the Golgi transport complex; midbody; and spindle. Colocalizes with the centrosome. Implicated in fibrosarcoma. Biomarker of Alzheimer's disease; bipolar disorder; pancreatic cancer; and rhinitis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CDC42Hs; cell division control protein 42 homolog; cell division cycle 42 (GTP binding protein, 25kDa); dJ224A6.1.1 (cell division cycle 42 (GTP-binding protein, 25kD)); dJ224A6.1.2 (cell division cycle 42 (GTP-binding protein, 25kD)); G25K; G25K GTP-binding protein; growth-regulating protein; GTP binding protein, 25kDa; GTP-binding protein, 25kD; small GTP binding protein CDC42; TKS
Orthologs:
Mus musculus (house mouse) : Cdc42 (cell division cycle 42)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cdc42 (cell division cycle 42)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdc42 (cell division cycle 42)
Pan paniscus (bonobo/pygmy chimpanzee) : CDC42 (cell division cycle 42)
Canis lupus familiaris (dog) : CDC42 (cell division cycle 42)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdc42 (cell division cycle 42)
Sus scrofa (pig) : CDC42 (cell division cycle 42)
more info ...
Related Pseudogenes: CDC42P1   CDC42P2   CDC42P3   CDC42P4   CDC42P5   CDC42P6  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38122,052,709 - 22,101,360 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37122,379,120 - 22,419,439 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36122,251,707 - 22,292,023 (+)NCBINCBI36hg18NCBI36
Build 34122,124,487 - 22,164,741NCBI
Celera120,702,109 - 20,742,389 (+)NCBI
Cytogenetic Map1p36.12NCBI
HuRef120,622,960 - 20,663,212 (+)NCBIHuRef
CHM1_1122,491,651 - 22,531,931 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CDC42
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 730976
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.