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Gene: IL1B (interleukin 1 beta) Homo sapiens
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Symbol: IL1B
Name: interleukin 1 beta
CRRD ID: 730981
Description: Exhibits cytokine activity; integrin binding activity; and protein domain specific binding activity. Involved in several processes, including positive regulation of macromolecule metabolic process; regulation of cellular biosynthetic process; and regulation of signal transduction. Localizes to extracellular space. Implicated in several diseases, including autoimmune disease (multiple); blood platelet disease (multiple); eye disease (multiple); gastrointestinal system cancer (multiple); and lung disease (multiple). Biomarker of several diseases, including artery disease (multiple); autoimmune disease (multiple); bronchial disease (multiple); lung disease (multiple); and nose disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: catabolin; IL-1; IL-1 beta; IL1-BETA; IL1beta; IL1F2; interleukin 1, beta; interleukin 1beta; interleukin-1 beta; preinterleukin 1 beta; pro-interleukin-1-beta
Orthologs:
Mus musculus (house mouse) : Il1b (interleukin 1 beta)  MGI  Alliance
Rattus norvegicus (Norway rat) : Il1b (interleukin 1 beta)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il1b (interleukin 1 beta)
Pan paniscus (bonobo/pygmy chimpanzee) : IL1B (interleukin 1 beta)
Canis lupus familiaris (dog) : IL1B (interleukin 1 beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il1b (interleukin 1 beta)
Sus scrofa (pig) : LOC110258578 (interleukin-1 beta-like)
Chlorocebus sabaeus (African green monkey) : IL1B (interleukin 1 beta)
Heterocephalus glaber (naked mole-rat) : Il1b (interleukin 1 beta)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Note: This gene has been reviewed for its involvement in coronavirus biology, and is involved in cytokine storm inflammatory response.
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2112,829,751 - 112,836,816 (-)EnsemblGRCh38hg38GRCh38
GRCh382112,829,751 - 112,836,843 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372113,587,337 - 113,594,356 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362113,303,808 - 113,310,827 (-)NCBINCBI36hg18NCBI36
Build 342113,303,567 - 113,310,587NCBI
Celera2106,972,536 - 106,979,555 (-)NCBI
Cytogenetic Map2q14.1NCBI
HuRef2106,041,964 - 106,048,983 (-)NCBIHuRef
CHM1_12113,591,491 - 113,598,510 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model