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Gene: CLCN3 (chloride voltage-gated channel 3) Homo sapiens
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Symbol: CLCN3
Name: chloride voltage-gated channel 3
Description: Exhibits PDZ domain binding activity; protein heterodimerization activity; and volume-sensitive chloride channel activity. Involved in chloride transmembrane transport and negative regulation of cell volume. Localizes to several cellular components, including the GABA-ergic synapse; cytoplasmic vesicle; and external side of plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: chloride channel 3; chloride channel protein 3; chloride channel, voltage-sensitive 3; chloride transporter ClC-3; ClC-3; CLC3; DKFZp564I0463; H(+)/Cl(-) exchange transporter 3
Orthologs:
Mus musculus (house mouse) : Clcn3 (chloride channel, voltage-sensitive 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Clcn3 (chloride voltage-gated channel 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Clcn3 (chloride voltage-gated channel 3)
Pan paniscus (bonobo/pygmy chimpanzee) : CLCN3 (chloride voltage-gated channel 3)
Canis lupus familiaris (dog) : CLCN3 (chloride voltage-gated channel 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Clcn3 (chloride voltage-gated channel 3)
Sus scrofa (pig) : CLCN3 (chloride voltage-gated channel 3)
more info ...
Related Pseudogenes: CLCN3P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384169,620,578 - 169,723,673 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh374170,541,672 - 170,644,338 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364170,778,297 - 170,878,732 (+)NCBINCBI36hg18NCBI36
Build 344170,916,451 - 171,016,886NCBI
Celera4167,874,695 - 167,975,138 (+)NCBI
Cytogenetic Map4q33NCBI
HuRef4166,296,448 - 166,399,155 (+)NCBIHuRef
CHM1_14170,518,267 - 170,620,908 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CLCN3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 730986
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.