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Gene: SLC4A7 (solute carrier family 4 member 7) Homo sapiens
Symbol: SLC4A7
Name: solute carrier family 4 member 7
Description: This locus encodes a sodium bicarbonate cotransporter. The encoded transmembrane protein appears to transport sodium and bicarbonate ions in a 1:1 ratio, and is thus considered an electroneutral cotransporter. The encoded protein likely plays a critical role in regulation of intracellular pH involved in visual and auditory sensory transmission. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Apr 2012]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: bicarbonate transporter; DKFZp686H168; electroneutral Na/HCO(3) cotransporter; NBC2; NBC3; NBCN1; SBC2; SLC4A6; sodium bicarbonate cotransporter 2; sodium bicarbonate cotransporter 2b; sodium bicarbonate cotransporter 3; solute carrier family 4, sodium bicarbonate cotransporter, member 7
Mus musculus (house mouse) : Slc4a7 (solute carrier family 4, sodium bicarbonate cotransporter, member 7)  MGI  Alliance
Rattus norvegicus (Norway rat) : Slc4a7 (solute carrier family 4 member 7)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc4a7 (solute carrier family 4 member 7)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC4A7 (solute carrier family 4 member 7)
Canis lupus familiaris (dog) : SLC4A7 (solute carrier family 4 member 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc4a7 (solute carrier family 4 member 7)
Sus scrofa (pig) : SLC4A7 (solute carrier family 4 member 7)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38327,372,721 - 27,484,420 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37327,414,212 - 27,525,911 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36327,389,218 - 27,473,249 (-)NCBINCBI36hg18NCBI36
Build 34327,389,217 - 27,473,249NCBI
Celera327,350,593 - 27,434,523 (-)NCBI
Cytogenetic Map3p24.1NCBI
HuRef327,357,387 - 27,468,725 (-)NCBIHuRef
CHM1_1327,364,200 - 27,475,895 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SLC4A7
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 730989
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2019-07-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.