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Gene: SLC4A7 (solute carrier family 4 member 7) Homo sapiens
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Symbol: SLC4A7
Name: solute carrier family 4 member 7
Description: This locus encodes a sodium bicarbonate cotransporter. The encoded transmembrane protein appears to transport sodium and bicarbonate ions in a 1:1 ratio, and is thus considered an electroneutral cotransporter. The encoded protein likely plays a critical role in regulation of intracellular pH involved in visual and auditory sensory transmission. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Apr 2012]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: bicarbonate transporter; DKFZp686H168; electroneutral Na/HCO(3) cotransporter; NBC2; NBC3; NBCN1; SBC2; SLC4A6; sodium bicarbonate cotransporter 2; sodium bicarbonate cotransporter 2b; sodium bicarbonate cotransporter 3; solute carrier family 4, sodium bicarbonate cotransporter, member 7
Orthologs:
Mus musculus (house mouse) : Slc4a7 (solute carrier family 4, sodium bicarbonate cotransporter, member 7)  MGI  Alliance
Rattus norvegicus (Norway rat) : Slc4a7 (solute carrier family 4 member 7)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc4a7 (solute carrier family 4 member 7)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC4A7 (solute carrier family 4 member 7)
Canis lupus familiaris (dog) : SLC4A7 (solute carrier family 4 member 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc4a7 (solute carrier family 4 member 7)
Sus scrofa (pig) : SLC4A7 (solute carrier family 4 member 7)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38327,372,721 - 27,484,420 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37327,414,212 - 27,525,911 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36327,389,218 - 27,473,249 (-)NCBINCBI36hg18NCBI36
Build 34327,389,217 - 27,473,249NCBI
Celera327,350,593 - 27,434,523 (-)NCBI
Cytogenetic Map3p24.1NCBI
HuRef327,357,387 - 27,468,725 (-)NCBIHuRef
CHM1_1327,364,200 - 27,475,895 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SLC4A7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 730989
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2019-07-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.