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Gene: CALCA (calcitonin related polypeptide alpha) Homo sapiens
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Symbol: CALCA
Name: calcitonin related polypeptide alpha
Description: Exhibits calcitonin receptor binding activity and identical protein binding activity. Involved in several processes, including G protein-coupled receptor signaling pathway; regulation of blood pressure; and regulation of myeloid leukocyte differentiation. Localizes to the cytoplasm and extracellular space. Implicated in migraine and osteoporosis. Biomarker of pyelonephritis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: alpha-type CGRP; CALC1; calcitonin; calcitonin 1; calcitonin gene-related peptide 1; calcitonin gene-related peptide I; calcitonin-related polypeptide alpha; calcitonin/calcitonin-related polypeptide, alpha; CGRP; CGRP-I; CGRP1; CT; katacalcin; KC; MGC126648; PCT
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1114,966,668 - 14,972,354 (-)Ensembl
GRCh381114,966,668 - 14,972,361 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371114,988,214 - 14,993,879 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361114,944,792 - 14,950,408 (-)NCBINCBI36hg18NCBI36
Build 341114,946,625 - 14,950,427NCBI
Celera1115,115,335 - 15,120,952 (-)NCBI
Cytogenetic Map11p15.2NCBI
HuRef1114,671,857 - 14,677,473 (-)NCBIHuRef
CHM1_11114,987,226 - 14,992,843 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CALCA
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 730992
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2020-01-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.