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Gene: ADORA2A (adenosine A2a receptor) Homo sapiens
Symbol: ADORA2A
Name: adenosine A2a receptor
CRRD ID: 730999
Description: Exhibits G protein-coupled adenosine receptor activity; enzyme binding activity; and identical protein binding activity. Involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Localizes to integral component of plasma membrane. Implicated in asthma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: A2aR; adenosine A2 receptor; adenosine receptor A2a; adenosine receptor subtype A2a; ADORA2; hA2aR; RDC8
Mus musculus (house mouse) : Adora2a (adenosine A2a receptor)  MGI  Alliance
Rattus norvegicus (Norway rat) : Adora2a (adenosine A2a receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adora2a (adenosine A2a receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : ADORA2A (adenosine A2a receptor)
Canis lupus familiaris (dog) : ADORA2A (adenosine A2a receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adora2a (adenosine A2a receptor)
Sus scrofa (pig) : ADORA2A (adenosine A2a receptor)
Chlorocebus sabaeus (African green monkey) : ADORA2A (adenosine A2a receptor)
Heterocephalus glaber (naked mole-rat) : Adora2a (adenosine A2a receptor)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2224,417,879 - 24,442,357 (+)EnsemblGRCh38hg38GRCh38
GRCh382224,423,597 - 24,442,357 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372224,819,565 - 24,838,328 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362223,153,530 - 23,168,325 (+)NCBINCBI36hg18NCBI36
Build 342223,153,645 - 23,162,878NCBI
Celera228,623,253 - 8,638,061 (+)NCBI
Cytogenetic Map22q11.23NCBI
HuRef227,769,458 - 7,788,241 (+)NCBIHuRef
CHM1_12224,778,238 - 24,796,999 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on ADORA2A
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 730999
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2020-11-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.