Gene: GNAI3 (G protein subunit alpha i3) Homo sapiens
Analyze
Symbol:
GNAI3
Name:
G protein subunit alpha i3
Description:
Exhibits GDP binding activity and GTPase activity. Involved in several processes, including GTP metabolic process; dopamine receptor signaling pathway; and positive regulation of macroautophagy. Localizes to several cellular components, including the centrosome; midbody; and plasma membrane. Colocalizes with the Golgi membrane and endoplasmic reticulum membrane.
Type:
protein-coding
RefSeq Status:
REVIEWED
Also known as:
87U6; ARCND1; FLJ26559; g(i) alpha-3; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3; guanine nucleotide-binding protein G(i) subunit alpha; guanine nucleotide-binding protein G(k) subunit alpha
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Mus musculus (house mouse):
Gnai3 (guanine nucleotide binding protein (G protein), alpha inhibiting 3)
HGNC
Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):
Gnai3 (G protein subunit alpha i3)
HGNC
Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Chinchilla lanigera (long-tailed chinchilla):
Gnai3 (G protein subunit alpha i3)
NCBI
Ortholog
Pan paniscus (bonobo/pygmy chimpanzee):
GNAI3 (G protein subunit alpha i3)
NCBI
Ortholog
Canis lupus familiaris (dog):
GNAI3 (G protein subunit alpha i3)
HGNC
Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Gnai3 (G protein subunit alpha i3)
NCBI
Ortholog
Sus scrofa (pig):
GNAI3 (G protein subunit alpha i3)
HGNC
Ensembl, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Other homologs 2
Mus musculus (house mouse):
Gnai1 (guanine nucleotide binding protein (G protein), alpha inhibiting 1)
HGNC
OrthoDB, OrthoMCL
Rattus norvegicus (Norway rat):
Gnai1 (G protein subunit alpha i1)
HGNC
OrthoDB
Rattus norvegicus (Norway rat):
Gnai2 (G protein subunit alpha i2)
HGNC
OrthoDB
Mus musculus (house mouse):
Gnai2 (guanine nucleotide binding protein (G protein), alpha inhibiting 2)
HGNC
OrthoDB
Sus scrofa (pig):
GNAI1 (G protein subunit alpha i1)
HGNC
OrthoDB
Sus scrofa (pig):
GNAI2 (G protein subunit alpha i2)
HGNC
OrthoDB
Alliance orthologs 3
Rattus norvegicus (Norway rat):
Gnai3 (G protein subunit alpha i3)
Alliance
DIOPT (HGNC, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, TreeFam)
Mus musculus (house mouse):
Gnai3 (guanine nucleotide binding protein (G protein), alpha inhibiting 3)
Alliance
DIOPT (HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam)
Danio rerio (zebrafish):
gnai3 (guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3)
Alliance
DIOPT (OrthoFinder, PANTHER, PhylomeDB, TreeFam, ZFIN)
Saccharomyces cerevisiae (baker's yeast):
GPA1
Alliance
DIOPT (Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PhylomeDB)
Drosophila melanogaster (fruit fly):
Galphai
Alliance
DIOPT (Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PhylomeDB, TreeFam)
Caenorhabditis elegans (roundworm):
gpa-16
Alliance
DIOPT (Hieranoid, OMA, OrthoFinder, PhylomeDB)
Caenorhabditis elegans (roundworm):
gpa-4
Alliance
DIOPT (OMA, OrthoFinder, PANTHER, PhylomeDB)
Allele / Splice:
See ClinVar data
Latest Assembly:
GRCh38 - Human Genome Assembly GRCh38
Position:
Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 1 109,548,615 - 109,600,195 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh37 1 110,091,186 - 110,138,465 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 1 109,892,824 - 109,938,498 (+) NCBI NCBI36 hg18 NCBI36 Build 34 1 109,803,342 - 109,849,017 NCBI Celera 1 108,360,485 - 108,407,751 (+) NCBI Cytogenetic Map 1 p13.3 NCBI HuRef 1 107,983,708 - 108,030,976 (+) NCBI HuRef CHM1_1 1 110,206,106 - 110,253,386 (+) NCBI CHM1_1
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Disease Annotations
Imported Annotations - ClinVar
Auriculocondylar Syndrome 1 IAGP RGD:8572646 8554872 ClinVar Annotator: match by term: Auriculocondylar syndrome 1 ClinVar PMID:23315542 Auriculocondylar Syndrome 1 IAGP RGD:13704782 8554872 ClinVar Annotator: match by term: Auriculocondylar syndrome 1 ClinVar PMID:25741868 Auriculocondylar Syndrome 1 IAGP RGD:8568942 8554872 ClinVar Annotator: match by term: Auriculocondylar syndrome 1 ClinVar PMID:11102934 , PMID:22560091 autistic disorder IAGP RGD:14351582 8554872 ClinVar Annotator: match by term: Autistic disorder of childhood onset ClinVar PMID:21681106 , PMID:30208311
Imported Annotations - CTD
amnestic disorder EXP 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:11350863 Auriculocondylar Syndrome EXP 11554173 CTD Direct Evidence: marker/mechanism CTD
Imported Annotations - OMIM
Auriculocondylar Syndrome 1 IAGP 7240710 OMIM
(+)-alpha-tocopherol multiple interactions ISO RGD:2714 6480464 alpha-Tocopherol inhibits the reaction [Glucose results in decreased expression of GNAI3 protein] CTD PMID:18441196 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one increases expression EXP 6480464 Metribolone results in increased expression of GNAI3 mRNA CTD PMID:16751804 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:731004 6480464 Tetrachlorodibenzodioxin results in increased expression of GNAI3 mRNA CTD PMID:19465110 2,6-dinitrotoluene affects expression ISO RGD:2714 6480464 2, 6-dinitrotoluene affects the expression of GNAI3 mRNA CTD PMID:21346803 2-hydroxypropanoic acid decreases expression EXP 6480464 Lactic Acid results in decreased expression of GNAI3 mRNA CTD PMID:30851411 3H-1,2-dithiole-3-thione decreases expression ISO RGD:2714 6480464 1, 2-dithiol-3-thione results in decreased expression of GNAI3 mRNA CTD PMID:19162173 7,9-dihydro-1H-purine-2,6,8(3H)-trione multiple interactions ISO RGD:2714 6480464 Uric Acid inhibits the reaction [Glucose results in decreased expression of GNAI3 protein] more ... CTD PMID:16962941 more ... 8-bromo-3',5'-cyclic AMP multiple interactions ISO RGD:2714 6480464 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of GNAI3 protein] CTD PMID:19252090 aldehydo-D-glucose multiple interactions ISO RGD:2714 6480464 Acetylcysteine inhibits the reaction [Glucose results in decreased expression of GNAI3 protein] more ... CTD PMID:18441196 aldehydo-D-glucose decreases expression ISO RGD:2714 6480464 Glucose results in decreased expression of GNAI3 protein CTD PMID:18441196 ammonium chloride affects expression ISO RGD:2714 6480464 Ammonium Chloride affects the expression of GNAI3 mRNA CTD PMID:16483693 amphetamine increases expression ISO RGD:2714 6480464 Amphetamine results in increased expression of GNAI3 mRNA CTD PMID:30779732 Aroclor 1254 decreases expression ISO RGD:731004 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of GNAI3 mRNA CTD PMID:23650126 Aroclor 1254 increases expression ISO RGD:731004 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of GNAI3 mRNA CTD PMID:25270620 arsenous acid increases expression EXP 6480464 Arsenic Trioxide results in increased expression of GNAI3 protein CTD PMID:25419056 benzo[a]pyrene affects methylation EXP 6480464 Benzo(a)pyrene affects the methylation of GNAI3 intron CTD PMID:30157460 biochanin A decreases expression EXP 6480464 biochanin A results in decreased expression of GNAI3 mRNA CTD PMID:12111696 bisphenol A increases expression ISO RGD:2714 6480464 bisphenol A results in increased expression of GNAI3 mRNA CTD PMID:25181051 bortezomib increases expression EXP 6480464 Bortezomib results in increased expression of GNAI3 mRNA CTD PMID:20977926 calciol increases expression ISO RGD:731004 6480464 Cholecalciferol results in increased expression of GNAI3 mRNA CTD PMID:16508948 carbon nanotube increases expression ISO RGD:731004 6480464 Nanotubes, Carbon results in increased expression of GNAI3 mRNA CTD PMID:25554681 chlorpyrifos decreases expression ISO RGD:2714 6480464 Chlorpyrifos results in decreased expression of GNAI3 mRNA CTD PMID:17452286 cholesterol multiple interactions EXP 6480464 Cholesterol inhibits the reaction [Progesterone results in decreased expression of GNAI3 protein] CTD PMID:19221014 clobetasol increases expression ISO RGD:731004 6480464 Clobetasol results in increased expression of GNAI3 mRNA CTD PMID:27462272 clofibrate decreases expression ISO RGD:731004 6480464 Clofibrate results in decreased expression of GNAI3 mRNA CTD PMID:17585979 clonidine affects response to substance ISO RGD:731004 6480464 GNAI3 affects the susceptibility to Clonidine CTD PMID:15207363 clonidine (amino form) affects response to substance ISO RGD:731004 6480464 GNAI3 affects the susceptibility to Clonidine CTD PMID:15207363 clonidine (imino form) affects response to substance ISO RGD:731004 6480464 GNAI3 affects the susceptibility to Clonidine CTD PMID:15207363 clozapine decreases expression ISO RGD:2714 6480464 Clozapine results in decreased expression of GNAI3 mRNA CTD PMID:15860345 cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of GNAI3 mRNA CTD PMID:19376846 Colforsin dapropate hydrochloride increases expression EXP 6480464 Colforsin results in increased expression of GNAI3 mRNA CTD PMID:16751804 copper(II) sulfate increases expression EXP 6480464 Copper Sulfate results in increased expression of GNAI3 mRNA CTD PMID:19549813 cyclosporin A increases expression EXP 6480464 Cyclosporine results in increased expression of GNAI3 mRNA CTD PMID:20106945 , PMID:25562108 D-glucose multiple interactions ISO RGD:2714 6480464 Acetylcysteine inhibits the reaction [Glucose results in decreased expression of GNAI3 protein] more ... CTD PMID:18441196 D-glucose decreases expression ISO RGD:2714 6480464 Glucose results in decreased expression of GNAI3 protein CTD PMID:18441196 dexamethasone increases expression ISO RGD:2714 6480464 Dexamethasone results in increased expression of GNAI3 mRNA CTD PMID:7730645 diarsenic trioxide increases expression EXP 6480464 Arsenic Trioxide results in increased expression of GNAI3 protein CTD PMID:25419056 diazinon decreases expression ISO RGD:2714 6480464 Diazinon results in decreased expression of GNAI3 mRNA CTD PMID:17452286 dibenziodolium multiple interactions ISO RGD:2714 6480464 diphenyleneiodonium affects the reaction [Glucose results in decreased expression of GNAI3 protein], diphenyleneiodonium inhibits the reaction [Streptozocin results in decreased expression of GNAI3 protein] CTD PMID:18441196 dibutyl phthalate increases expression ISO RGD:731004 6480464 Dibutyl Phthalate results in increased expression of GNAI3 mRNA CTD PMID:21266533 dicrotophos decreases expression EXP 6480464 dicrotophos results in decreased expression of GNAI3 mRNA CTD PMID:28302478 diuron decreases expression ISO RGD:2714 6480464 Diuron results in decreased expression of GNAI3 mRNA CTD PMID:25152437 doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of GNAI3 mRNA CTD PMID:29803840 ethanol affects splicing ISO RGD:731004 6480464 Ethanol affects the splicing of GNAI3 mRNA CTD PMID:30319688 flutamide increases expression ISO RGD:2714 6480464 Flutamide results in increased expression of GNAI3 mRNA CTD PMID:24136188 genistein multiple interactions ISO RGD:2714 6480464 [Genistein co-treated with Methoxychlor] results in decreased expression of GNAI3 mRNA CTD PMID:21782745 gentamycin increases expression ISO RGD:2714 6480464 Gentamicins results in increased expression of GNAI3 mRNA CTD PMID:22061828 glucose multiple interactions ISO RGD:2714 6480464 Acetylcysteine inhibits the reaction [Glucose results in decreased expression of GNAI3 protein] more ... CTD PMID:18441196 glucose decreases expression ISO RGD:2714 6480464 Glucose results in decreased expression of GNAI3 protein CTD PMID:18441196 Guanabenz affects response to substance ISO RGD:731004 6480464 GNAI3 affects the susceptibility to Guanabenz CTD PMID:15207363 haloperidol decreases expression ISO RGD:2714 6480464 Haloperidol results in decreased expression of GNAI3 mRNA CTD PMID:15860345 hypochlorous acid increases expression ISO RGD:731004 6480464 Hypochlorous Acid results in increased expression of GNAI3 mRNA CTD PMID:19376150 lipopolysaccharide increases activity ISO RGD:731004 6480464 Lipopolysaccharides results in increased activity of GNAI3 protein CTD PMID:21255617 methoxychlor multiple interactions ISO RGD:2714 6480464 [Genistein co-treated with Methoxychlor] results in decreased expression of GNAI3 mRNA CTD PMID:21782745 N-acetyl-L-cysteine multiple interactions ISO RGD:2714 6480464 Acetylcysteine inhibits the reaction [Glucose results in decreased expression of GNAI3 protein], Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of GNAI3 protein] CTD PMID:18441196 N-methyl-4-phenylpyridinium increases expression ISO RGD:731004 6480464 1-Methyl-4-phenylpyridinium results in increased expression of GNAI3 protein CTD PMID:26558463 nefazodone increases expression ISO RGD:2714 6480464 nefazodone results in increased expression of GNAI3 mRNA CTD PMID:24136188 nitroprusside decreases expression ISO RGD:2714 6480464 Nitroprusside results in decreased expression of GNAI3 protein CTD PMID:16962941 paracetamol affects expression ISO RGD:731004 6480464 Acetaminophen affects the expression of GNAI3 mRNA CTD PMID:17562736 paraquat increases expression ISO RGD:2714 6480464 Paraquat results in increased expression of GNAI3 mRNA CTD PMID:17077588 pentachlorophenol increases expression ISO RGD:731004 6480464 Pentachlorophenol results in increased expression of GNAI3 mRNA CTD PMID:23892564 peroxynitrous acid multiple interactions ISO RGD:2714 6480464 manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Peroxynitrous Acid results in decreased expression of GNAI3 protein], Uric Acid inhibits the reaction [Peroxynitrous Acid results in decreased expression of GNAI3 protein] CTD PMID:18055527 peroxynitrous acid decreases expression ISO RGD:2714 6480464 Peroxynitrous Acid results in decreased expression of GNAI3 protein CTD PMID:18055527 phenobarbital affects expression ISO RGD:731004 6480464 Phenobarbital affects the expression of GNAI3 mRNA CTD PMID:23091169 potassium dichromate increases expression EXP 6480464 Potassium Dichromate results in increased expression of GNAI3 protein CTD PMID:23718831 progesterone multiple interactions EXP 6480464 CAV3 mutant form inhibits the reaction [Progesterone results in decreased expression of GNAI3 protein], Cholesterol inhibits the reaction [Progesterone results in decreased expression of GNAI3 protein] CTD PMID:19221014 progesterone decreases expression EXP 6480464 Progesterone results in decreased expression of GNAI3 protein CTD PMID:19221014 quercetin increases expression ISO RGD:2714 6480464 Quercetin results in increased expression of GNAI3 protein CTD PMID:9590266 rac-lactic acid decreases expression EXP 6480464 Lactic Acid results in decreased expression of GNAI3 mRNA CTD PMID:30851411 reserpine increases expression ISO RGD:2714 6480464 Reserpine results in increased expression of GNAI3 protein CTD PMID:11264240 S-nitroso-N-acetyl-D-penicillamine decreases expression ISO RGD:2714 6480464 S-Nitroso-N-Acetylpenicillamine results in decreased expression of GNAI3 protein CTD PMID:16962941 , PMID:19252090 S-nitroso-N-acetyl-D-penicillamine multiple interactions ISO RGD:2714 6480464 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of GNAI3 protein] more ... CTD PMID:16962941 , PMID:19252090 SB 431542 increases expression EXP 6480464 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of GNAI3 protein CTD PMID:25670856 Soman increases expression ISO RGD:2714 6480464 Soman results in increased expression of GNAI3 mRNA CTD PMID:19281266 streptozocin decreases expression ISO RGD:2714 6480464 Streptozocin results in decreased expression of GNAI3 protein CTD PMID:18441196 streptozocin multiple interactions ISO RGD:2714 6480464 Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of GNAI3 protein], diphenyleneiodonium inhibits the reaction [Streptozocin results in decreased expression of GNAI3 protein] CTD PMID:18441196 trichostatin A affects expression EXP 6480464 trichostatin A affects the expression of GNAI3 mRNA CTD PMID:28542535 valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of GNAI3 mRNA CTD PMID:23179753 valproic acid affects expression EXP 6480464 Valproic Acid affects the expression of GNAI3 mRNA CTD PMID:25979313 vitamin E multiple interactions ISO RGD:2714 6480464 alpha-Tocopherol inhibits the reaction [Glucose results in decreased expression of GNAI3 protein] CTD PMID:18441196
Biological Process
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway IDA 2290271 (PMID:19478087) UniProtKB PMID:19478087 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway TAS 2290271 Reactome Reactome:R-HSA-170670 adenylate cyclase-modulating G protein-coupled receptor signaling pathway IBA MGI:MGI:95768 more ... 2290271 (PMID:21873635) GO_Central PMID:21873635 brain development IEA UniProtKB:P08753 , ensembl:ENSRNOP000000267102290271 Ensembl GO_REF:0000107 cell division IDA 2290271 (PMID:17635935) UniProtKB PMID:17635935 dopamine receptor signaling pathway IDA 2290271 (PMID:19478087) UniProtKB PMID:19478087 G protein-coupled receptor signaling pathway TAS 2290271 Reactome Reactome:R-HSA-388396 GTP metabolic process IDA 2290271 (PMID:19478087) UniProtKB PMID:19478087 negative regulation of adenylate cyclase activity TAS 2290271 (PMID:7608168) PINC PMID:7608168 negative regulation of apoptotic signaling pathway IEA UniProtKB:P08753 , ensembl:ENSRNOP000000267102290271 Ensembl GO_REF:0000107 positive regulation of macroautophagy IMP 2290271 (PMID:12642577) UniProtKB PMID:12642577 positive regulation of NAD(P)H oxidase activity IEA UniProtKB:P08753 , ensembl:ENSRNOP000000267102290271 Ensembl GO_REF:0000107 positive regulation of superoxide anion generation IEA UniProtKB:P08753 , ensembl:ENSRNOP000000267102290271 Ensembl GO_REF:0000107 positive regulation of vascular smooth muscle cell proliferation IEA UniProtKB:P08753 , ensembl:ENSRNOP000000267102290271 Ensembl GO_REF:0000107 protein folding TAS 2290271 Reactome Reactome:R-HSA-390466 vesicle fusion IEA UniProtKB:P08753 , ensembl:ENSRNOP000000267102290271 Ensembl GO_REF:0000107
Cellular Component
centrosome IDA 2290271 (PMID:17635935) UniProt PMID:17635935 cytoplasm IDA 2290271 (PMID:17635935) UniProtKB PMID:17635935 endoplasmic reticulum membrane colocalizes_with IDA 2290271 (PMID:12642577) UniProtKB PMID:12642577 extracellular exosome HDA 2290271 (PMID:19056867), (PMID:20458337) UniProtKB PMID:19056867 , PMID:20458337 Golgi membrane colocalizes_with IDA 2290271 (PMID:12642577) UniProtKB PMID:12642577 heterotrimeric G-protein complex IBA FB:FBgn0001122 more ... 2290271 (PMID:21873635) GO_Central PMID:21873635 lysosomal membrane HDA 2290271 (PMID:17897319) UniProtKB PMID:17897319 membrane HDA 2290271 (PMID:19946888) UniProtKB PMID:19946888 membrane raft IEA UniProtKB:P08753 , ensembl:ENSRNOP000000267102290271 Ensembl GO_REF:0000107 midbody IDA 2290271 (PMID:17635935) UniProtKB PMID:17635935 plasma membrane IDA 2290271 (PMID:17635935), (PMID:27864364) UniProt PMID:17635935 , PMID:27864364 plasma membrane TAS 2290271 Reactome Reactome:R-HSA-111879 more ... zymogen granule IEA UniProtKB:P08753 , ensembl:ENSRNOP000000267102290271 Ensembl GO_REF:0000107
Molecular Function
G protein-coupled receptor binding IBA MGI:MGI:95770 more ... 2290271 (PMID:21873635) GO_Central PMID:21873635 G protein-coupled serotonin receptor binding IEA UniProtKB:P08753 , ensembl:ENSRNOP000000267102290271 Ensembl GO_REF:0000107 G-protein beta/gamma-subunit complex binding IBA MGI:MGI:95778 , PANTHER:PTN000026392 2290271 (PMID:21873635) GO_Central PMID:21873635 GDP binding IDA 2290271 (PMID:19478087) UniProtKB PMID:19478087 GTP binding IEA UniProtKB-KW:KW-0342 2290271 UniProt GO_REF:0000037 GTPase activating protein binding IEA UniProtKB:P08753 , ensembl:ENSRNOP000000267102290271 Ensembl GO_REF:0000107 GTPase activity IDA 2290271 (PMID:19478087) UniProtKB PMID:19478087 GTPase activity IBA FB:FBgn0004435 more ... 2290271 (PMID:21873635) GO_Central PMID:21873635 metal ion binding IEA UniProtKB-KW:KW-0479 2290271 UniProtKB GO_REF:0000037 protein binding IPI UniProtKB:O43665 2290271 (PMID:18434541) UniProtKB PMID:18434541 protein binding IPI UniProtKB:Q8IVA1 2290271 (PMID:28514442) IntAct PMID:28514442 protein binding IPI UniProtKB:Q9BRC7-1 2290271 (PMID:30194280) UniProt PMID:30194280 protein binding IPI UniProtKB:Q9BRC7-2 2290271 (PMID:30194280) UniProt PMID:30194280 protein binding IPI UniProtKB:Q9P219 2290271 (PMID:26126266) UniProt PMID:26126266 protein binding IPI UniProtKB:O43566 2290271 (PMID:21988832) IntAct PMID:21988832 protein binding IPI UniProtKB:Q9Y4H4 2290271 (PMID:25416956) IntAct PMID:25416956 protein binding IPI UniProtKB:Q9UGC6 2290271 (PMID:25416956) IntAct PMID:25416956 protein binding IPI UniProtKB:Q3V6T2 2290271 (PMID:27621449) UniProt PMID:27621449 protein domain specific binding IEA UniProtKB:P08753 , ensembl:ENSRNOP000000267102290271 Ensembl GO_REF:0000107