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Gene: TACR1 (tachykinin receptor 1) Homo sapiens
Symbol: TACR1
Name: tachykinin receptor 1
CRRD ID: 731008
Description: Exhibits substance P receptor activity. Involved in positive regulation of cytosolic calcium ion concentration; positive regulation of flagellated sperm motility; and tachykinin receptor signaling pathway. Localizes to plasma membrane; sperm head; and sperm midpiece. Biomarker of asthma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: neurokinin 1 receptor; NK-1 receptor; NK-1R; NK1R; NKIR; SPR; substance-P receptor; TAC1R; tachykinin 1 receptor (substance P receptor, neurokinin 1 receptor); tachykinin receptor 1 (substance P receptor, neurokinin-1 receptor)
Mus musculus (house mouse) : Tacr1 (tachykinin receptor 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tacr1 (tachykinin receptor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tacr1 (tachykinin receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TACR1 (tachykinin receptor 1)
Canis lupus familiaris (dog) : TACR1 (tachykinin receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tacr1 (tachykinin receptor 1)
Sus scrofa (pig) : TACR1 (tachykinin receptor 1)
Chlorocebus sabaeus (African green monkey) : TACR1 (tachykinin receptor 1)
Heterocephalus glaber (naked mole-rat) : Tacr1 (tachykinin receptor 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl275,046,463 - 75,199,520 (-)EnsemblGRCh38hg38GRCh38
GRCh38275,046,463 - 75,199,520 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37275,273,590 - 75,426,645 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36275,129,738 - 75,279,781 (-)NCBINCBI36hg18NCBI36
Build 34275,189,817 - 75,337,838NCBI
Celera275,104,880 - 75,257,954 (-)NCBI
Cytogenetic Map2p12NCBI
HuRef275,010,440 - 75,164,411 (-)NCBIHuRef
CHM1_1275,202,888 - 75,356,007 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on TACR1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731008
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2020-10-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.