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Gene: Ccn2 (cellular communication network factor 2) Mus musculus
Symbol: Ccn2
Name: cellular communication network factor 2
Description: Exhibits heparin binding activity and integrin binding activity. Involved in several processes, including cartilage condensation; cell surface receptor signaling pathway; and chondrocyte proliferation. Localizes to extracellular matrix. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; respiratory system; and skeleton. Orthologous to human CCN2 (cellular communication network factor 2); PARTICIPATES IN transforming growth factor-beta Smad dependent signaling pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; 1-octadec-9-enoylglycero-3-phosphate; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CCN family member 2; cellular communication network factor 1; connective tissue growth factor; Connective tissue growth factor precursor (CTGF) (FISP-12 protein) (Hypertrophic chondrocyte-specific protein 24); Ctgf; fibroblast inducible secreated protein; fibroblast inducible secreted protein; fisp-12; Fisp12; Hcs24; hypertrophic chondrocyte-specific gene product 24; hypertrophic chondrocyte-specific protein 24
Homo sapiens (human) : CCN2 (cellular communication network factor 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ccn2 (cellular communication network factor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ccn2 (cellular communication network factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CCN2 (cellular communication network factor 2)
Canis lupus familiaris (dog) : CCN2 (cellular communication network factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ccn2 (cellular communication network factor 2)
Sus scrofa (pig) : CCN2 (cellular communication network factor 2)
Chlorocebus sabaeus (African green monkey) : CCN2 (cellular communication network factor 2)
Heterocephalus glaber (naked mole-rat) : Ccn2 (cellular communication network factor 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1024,595,442 - 24,598,683 (+)EnsemblGRCm38mm10GRCm38
GRCm381024,595,442 - 24,598,683 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371024,315,248 - 24,318,489 (+)NCBIGRCm37mm9NCBIm37
MGSCv361024,284,923 - 24,288,096 (+)NCBImm8
Celera1025,537,033 - 25,540,272 (+)NCBICelera
Cytogenetic Map10A4NCBI
cM Map1011.84NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Ccn2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731014
Created: 2003-12-10
Species: Mus musculus
Last Modified: 2020-05-19
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.