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Gene: BDNF (brain derived neurotrophic factor) Homo sapiens
Symbol: BDNF
Name: brain derived neurotrophic factor
Description: Predicted to have growth factor activity. Involved in nervous system development; positive regulation of receptor binding activity; and positive regulation of synapse assembly. Localizes to the mitochondrion and nuclear speck. Implicated in several diseases, including cognitive disorder (multiple); congenital central hypoventilation syndrome; neurodegenerative disease (multiple); obstructive sleep apnea; and status epilepticus. Biomarker of several diseases, including autoimmune hypersensitivity disease (multiple); eye disease (multiple); lung disease (multiple); mental depression (multiple); and neurodegenerative disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: abrineurin; ANON2; brain-derived neurotrophic factor; BULN2; MGC34632; neurotrophin
Mus musculus (house mouse) : Bdnf (brain derived neurotrophic factor)  MGI  Alliance
Rattus norvegicus (Norway rat) : Bdnf (brain-derived neurotrophic factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bdnf (brain derived neurotrophic factor)
Pan paniscus (bonobo/pygmy chimpanzee) : BDNF (brain derived neurotrophic factor)
Canis lupus familiaris (dog) : BDNF (brain derived neurotrophic factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bdnf (brain derived neurotrophic factor)
Sus scrofa (pig) : BDNF (brain derived neurotrophic factor)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1127,654,893 - 27,722,058 (-)Ensembl
GRCh381127,654,893 - 27,722,030 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371127,676,440 - 27,743,605 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361127,633,016 - 27,699,872 (-)NCBINCBI36hg18NCBI36
Build 341127,633,019 - 27,637,249NCBI
Celera1127,822,548 - 27,889,725 (-)NCBI
Cytogenetic Map11p14.1NCBI
HuRef1127,374,586 - 27,441,772 (-)NCBIHuRef
CHM1_11127,675,184 - 27,742,527 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences