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Gene: SGK1 (serum/glucocorticoid regulated kinase 1) Homo sapiens
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Symbol: SGK1
Name: serum/glucocorticoid regulated kinase 1
Description: Exhibits protein serine/threonine/tyrosine kinase activity. Predicted to be involved in intracellular signal transduction; neuron projection morphogenesis; and peptidyl-serine phosphorylation. Localizes to the cytosol and nuclear speck. Implicated in hypertension. Biomarker of granulosa cell tumor; mucinous cystadenocarcinoma; and serous cystadenocarcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: serine/threonine protein kinase SGK; serine/threonine-protein kinase Sgk1; serum/glucocorticoid-regulated kinase 1; SGK; Sgk1 variant i3
Orthologs:
Mus musculus (house mouse) : Sgk1 (serum/glucocorticoid regulated kinase 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sgk1 (serum/glucocorticoid regulated kinase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sgk1 (serum/glucocorticoid regulated kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SGK1 (serum/glucocorticoid regulated kinase 1)
Canis lupus familiaris (dog) : SGK1 (serum/glucocorticoid regulated kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sgk1 (serum/glucocorticoid regulated kinase 1)
Sus scrofa (pig) : SGK1 (serum/glucocorticoid regulated kinase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386134,169,246 - 134,318,112 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh376134,490,384 - 134,639,196 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366134,532,081 - 134,537,695 (-)NCBINCBI36hg18NCBI36
Build 346134,532,081 - 134,537,695NCBI
Celera6135,231,367 - 135,380,168 (-)NCBI
Cytogenetic Map6q23.2NCBI
HuRef6132,059,144 - 132,203,585 (-)NCBIHuRef
CHM1_16134,752,625 - 134,901,421 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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Disease Annotations
Gene-Chemical Interaction Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on SGK1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731028
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.