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Gene: RGS3 (regulator of G protein signaling 3) Homo sapiens
Symbol: RGS3
Name: regulator of G protein signaling 3
Description: Predicted to have GTPase activator activity and GTPase activity. Predicted to be involved in G protein-coupled receptor signaling pathway; inactivation of MAPK activity; and regulation of G protein-coupled receptor signaling pathway. Localizes to the plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C2PA; FLJ20370; FLJ31516; FLJ90496; PDZ-RGS3; regulator of G-protein signaling 3; regulator of G-protein signalling 3; RGP3
Mus musculus (house mouse) : Rgs3 (regulator of G-protein signaling 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rgs3 (regulator of G-protein signaling 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rgs3 (regulator of G protein signaling 3)
Pan paniscus (bonobo/pygmy chimpanzee) : RGS3 (regulator of G protein signaling 3)
Canis lupus familiaris (dog) : RGS3 (regulator of G protein signaling 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rgs3 (regulator of G protein signaling 3)
Sus scrofa (pig) : RGS3 (regulator of G protein signaling 3)
Chlorocebus sabaeus (African green monkey) : RGS3 (regulator of G protein signaling 3)
Heterocephalus glaber (naked mole-rat) : Rgs3 (regulator of G protein signaling 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl9113,444,731 - 113,597,743 (+)EnsemblGRCh38hg38GRCh38
GRCh389113,444,730 - 113,597,743 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh379116,207,009 - 116,360,023 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369115,246,832 - 115,399,839 (+)NCBINCBI36hg18NCBI36
Build 349113,435,753 - 113,439,571NCBI
Celera986,854,611 - 87,007,602 (+)NCBI
Cytogenetic Map9q32NCBI
HuRef985,813,933 - 85,966,662 (+)NCBIHuRef
CHM1_19116,353,638 - 116,506,463 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on RGS3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731031
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2020-03-10
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.