Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Dffb (DNA fragmentation factor, beta subunit) Mus musculus
Analyze
Symbol: Dffb
Name: DNA fragmentation factor, beta subunit
Description: Exhibits DNA binding activity and nuclease activity. Predicted to be involved in apoptotic DNA fragmentation; apoptotic chromosome condensation; and protein homooligomerization. Predicted to localize to the cytosol and nuclear lumen. Orthologous to human DFFB (DNA fragmentation factor subunit beta); PARTICIPATES IN apoptotic cell death pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1; cisplatin.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 40kDa; 5730477D02Rik; CAD; caspase-activated deoxyribonuclease; caspase-activated DNase; CPAN; DFF-40; DFF40; Didff; DNA fragmentation factor 40 kDa subunit; DNA fragmentation factor subunit beta; DNA fragmentation factor, 40 kD, beta subunit; DNase inhibited by DNA fragmentation factor
Orthologs:
Homo sapiens (human) : DFFB (DNA fragmentation factor subunit beta)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dffb (DNA fragmentation factor subunit beta)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dffb (DNA fragmentation factor subunit beta)
Pan paniscus (bonobo/pygmy chimpanzee) : DFFB (DNA fragmentation factor subunit beta)
Canis lupus familiaris (dog) : DFFB (DNA fragmentation factor subunit beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dffb (DNA fragmentation factor subunit beta)
Sus scrofa (pig) : DFFB (DNA fragmentation factor subunit beta)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm384153,964,447 - 153,975,121 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374153,338,558 - 153,349,190 (-)NCBIGRCm37mm9NCBIm37
MGSCv364152,808,255 - 152,818,926 (-)NCBImm8
Celera4156,252,603 - 156,263,261 (-)NCBICelera
Cytogenetic Map4 E2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Dffb
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731034
Created: 2003-12-10
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.