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Gene: CIT (citron rho-interacting serine/threonine kinase) Homo sapiens
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Symbol: CIT
Name: citron rho-interacting serine/threonine kinase
Description: Exhibits PDZ domain binding activity and scaffold protein binding activity. Involved in mitotic cytokinesis; neuron apoptotic process; and positive regulation of cytokinesis. Localizes to the membrane. Implicated in primary autosomal recessive microcephaly 17.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CITK; citron (rho-interacting, serine/threonine kinase 21); citron Rho-interacting kinase; CRIK; KIAA0949; MCPH17; rho-interacting, serine/threonine kinase 21; serine/threonine kinase 21; serine/threonine-protein kinase 21; STK21
Orthologs:
Mus musculus (house mouse) : Cit (citron)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cit (citron rho-interacting serine/threonine kinase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cit (citron rho-interacting serine/threonine kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : CIT (citron rho-interacting serine/threonine kinase)
Canis lupus familiaris (dog) : CIT (citron rho-interacting serine/threonine kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cit (citron rho-interacting serine/threonine kinase)
Sus scrofa (pig) : CIT (citron rho-interacting serine/threonine kinase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812119,685,791 - 119,877,320 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712120,123,595 - 120,315,095 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612118,607,981 - 118,799,475 (-)NCBINCBI36hg18NCBI36
Build 3412118,586,317 - 118,777,812NCBI
Celera12119,756,651 - 119,948,207 (-)NCBI
Cytogenetic Map12q24.23NCBI
HuRef12117,131,727 - 117,325,161 (-)NCBIHuRef
CHM1_112120,091,103 - 120,282,752 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CIT
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731048
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.