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Gene: Dgat1 (diacylglycerol O-acyltransferase 1) Mus musculus
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Symbol: Dgat1
Name: diacylglycerol O-acyltransferase 1
Description: Exhibits 2-acylglycerol O-acyltransferase activity and diacylglycerol O-acyltransferase activity. Involved in several processes, including acylglycerol metabolic process; fatty acid homeostasis; and long-chain fatty-acyl-CoA metabolic process. Localizes to the integral component of membrane and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in cardiomyopathy; congenital diarrhea; and congenital diarrhea 7 with exudative enteropathy. Is expressed in several structures, including brain; genitourinary system; integument; liver; and yolk sac. Orthologous to human DGAT1 (diacylglycerol O-acyltransferase 1); PARTICIPATES IN retinol metabolic pathway; vitamin A deficiency pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: acyl-CoA retinol O-fatty-acyltransferase; ARAT; C75990; D15Ertd23e; Dgat; diacylglycerol acyltransferase 1; diglyceride acyltransferase; retinol O-fatty-acyltransferase
Orthologs:
Homo sapiens (human) : DGAT1 (diacylglycerol O-acyltransferase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dgat1 (diacylglycerol O-acyltransferase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dgat1 (diacylglycerol O-acyltransferase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DGAT1 (diacylglycerol O-acyltransferase 1)
Canis lupus familiaris (dog) : DGAT1 (diacylglycerol O-acyltransferase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dgat1 (diacylglycerol O-acyltransferase 1)
Sus scrofa (pig) : DGAT1 (diacylglycerol O-acyltransferase 1)
Chlorocebus sabaeus (African green monkey) : DGAT1 (diacylglycerol O-acyltransferase 1)
Heterocephalus glaber (naked mole-rat) : Dgat1 (diacylglycerol O-acyltransferase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1576,502,015 - 76,511,953 (-)Ensembl
GRCm381576,502,012 - 76,512,021 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371576,332,445 - 76,342,248 (-)NCBIGRCm37mm9NCBIm37
MGSCv361576,329,270 - 76,339,073 (-)NCBImm8
Celera1578,002,555 - 78,012,327 (-)NCBICelera
Cytogenetic Map15D3NCBI
cM Map1535.99NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Dgat1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731053
Created: 2003-12-10
Species: Mus musculus
Last Modified: 2020-02-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.