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Gene: Dgat1 (diacylglycerol O-acyltransferase 1) Mus musculus
Symbol: Dgat1
Name: diacylglycerol O-acyltransferase 1
Description: Exhibits 2-acylglycerol O-acyltransferase activity and diacylglycerol O-acyltransferase activity. Involved in several processes, including acylglycerol metabolic process; fatty acid homeostasis; and long-chain fatty-acyl-CoA metabolic process. Localizes to the integral component of membrane and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in cardiomyopathy; congenital diarrhea; and congenital diarrhea 7 with exudative enteropathy. Is expressed in several structures, including brain; genitourinary system; integument; liver; and yolk sac. Orthologous to human DGAT1 (diacylglycerol O-acyltransferase 1); PARTICIPATES IN retinol metabolic pathway; vitamin A deficiency pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: acyl-CoA retinol O-fatty-acyltransferase; ARAT; C75990; D15Ertd23e; Dgat; diacylglycerol acyltransferase 1; diglyceride acyltransferase; retinol O-fatty-acyltransferase
Homo sapiens (human) : DGAT1 (diacylglycerol O-acyltransferase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dgat1 (diacylglycerol O-acyltransferase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dgat1 (diacylglycerol O-acyltransferase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DGAT1 (diacylglycerol O-acyltransferase 1)
Canis lupus familiaris (dog) : DGAT1 (diacylglycerol O-acyltransferase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dgat1 (diacylglycerol O-acyltransferase 1)
Sus scrofa (pig) : DGAT1 (diacylglycerol O-acyltransferase 1)
Chlorocebus sabaeus (African green monkey) : DGAT1 (diacylglycerol O-acyltransferase 1)
Heterocephalus glaber (naked mole-rat) : Dgat1 (diacylglycerol O-acyltransferase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1576,502,015 - 76,511,953 (-)Ensembl
GRCm381576,502,012 - 76,512,021 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371576,332,445 - 76,342,248 (-)NCBIGRCm37mm9NCBIm37
MGSCv361576,329,270 - 76,339,073 (-)NCBImm8
Celera1578,002,555 - 78,012,327 (-)NCBICelera
Cytogenetic Map15D3NCBI
cM Map1535.99NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Dgat1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731053
Created: 2003-12-10
Species: Mus musculus
Last Modified: 2020-02-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.