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Gene: BHLHE41 (basic helix-loop-helix family member e41) Homo sapiens
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Symbol: BHLHE41
Name: basic helix-loop-helix family member e41
Description: Exhibits several functions, including E-box binding activity; protein heterodimerization activity; and transcription corepressor activity. Involved in negative regulation of transcription by RNA polymerase II. Predicted to localize to the nuclear chromatin. Implicated in sleep disorder.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: basic helix-loop-helix domain containing, class B, 3; basic helix-loop-helix family, member e41; BHLHB3; class E basic helix-loop-helix protein 41; DEC2; differentially expressed in chondrocytes 2; differentially expressed in chondrocytes protein 2; enhancer-of-split and hairy-related protein 1; FNSS1; hDEC2; SHARP-1; SHARP1
Orthologs:
Mus musculus (house mouse) : Bhlhe41 (basic helix-loop-helix family, member e41)  MGI  Alliance
Rattus norvegicus (Norway rat) : Bhlhe41 (basic helix-loop-helix family, member e41)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bhlhe41 (basic helix-loop-helix family member e41)
Pan paniscus (bonobo/pygmy chimpanzee) : BHLHE41 (basic helix-loop-helix family member e41)
Canis lupus familiaris (dog) : BHLHE41 (basic helix-loop-helix family member e41)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bhlhe41 (basic helix-loop-helix family member e41)
Sus scrofa (pig) : BHLHE41 (basic helix-loop-helix family member e41)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381226,120,030 - 26,125,037 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371226,272,959 - 26,278,003 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361226,164,226 - 26,169,113 (-)NCBINCBI36hg18NCBI36
Build 341226,164,227 - 26,169,113NCBI
Celera1231,419,506 - 31,424,550 (-)NCBI
Cytogenetic Map12p12.1NCBI
HuRef1226,043,295 - 26,047,960 (-)NCBIHuRef
CHM1_11226,237,976 - 26,243,020 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on BHLHE41
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731061
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.