Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: KCNA5 (potassium voltage-gated channel subfamily A member 5) Homo sapiens
Analyze
Symbol: KCNA5
Name: potassium voltage-gated channel subfamily A member 5
CRRD ID: 731065
Description: Exhibits several functions, including alpha-actinin binding activity; scaffold protein binding activity; and voltage-gated potassium channel activity. Involved in several processes, including cardiac conduction; membrane hyperpolarization; and regulation of ion transport. Localizes to several cellular components, including intercalated disc; membrane raft; and voltage-gated potassium channel complex. Predicted to colocalize with caveola. Implicated in familial atrial fibrillation and pulmonary hypertension. Biomarker of pulmonary hypertension and stomach cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ATFB7; cardiac potassium channel; HCK1; HK2; HPCN1; insulinoma and islet potassium channel; KV1.5; MGC117058; MGC117059; PCN1; potassium channel 1; potassium channel protein; potassium channel, voltage gated shaker related subfamily A, member 5; potassium voltage-gated channel, shaker-related subfamily, member 5; voltage-gated potassium channel HK2; voltage-gated potassium channel protein Kv1.5; voltage-gated potassium channel subunit Kv1.5
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl125,043,879 - 5,046,788 (+)EnsemblGRCh38hg38GRCh38
GRCh38125,043,879 - 5,046,788 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37125,153,085 - 5,155,954 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36125,023,346 - 5,026,210 (+)NCBINCBI36hg18NCBI36
Build 34125,023,345 - 5,026,210NCBI
Celera126,774,165 - 6,777,029 (+)NCBI
Cytogenetic Map12p13.32NCBI
HuRef125,009,439 - 5,012,308 (+)NCBIHuRef
CHM1_1125,152,272 - 5,155,141 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on KCNA5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731065
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2020-09-23
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.