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Gene: CSF1 (colony stimulating factor 1) Homo sapiens
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Symbol: CSF1
Name: colony stimulating factor 1
Description: Exhibits cytokine activity; growth factor activity; and protein homodimerization activity. Involved in several processes, including positive regulation of cell differentiation; positive regulation of macromolecule metabolic process; and positive regulation of macrophage chemotaxis. Localizes to several cellular components, including the extracellular space; nuclear body; and perinuclear region of cytoplasm. Implicated in interstitial cystitis. Biomarker of several diseases, including amyloidosis; atherosclerosis; end stage renal failure; glomerulonephritis (multiple); and vesicoureteral reflux.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: colony stimulating factor 1 (macrophage); CSF-1; lanimostim; macrophage colony stimulating factor; macrophage colony stimulating factor 1; macrophage colony-stimulating factor 1; MCSF; MGC31930
Orthologs:
Mus musculus (house mouse) : Csf1 (colony stimulating factor 1 (macrophage))  MGI  Alliance
Rattus norvegicus (Norway rat) : Csf1 (colony stimulating factor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Csf1 (colony stimulating factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CSF1 (colony stimulating factor 1)
Canis lupus familiaris (dog) : CSF1 (colony stimulating factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Csf1 (colony stimulating factor 1)
Sus scrofa (pig) : CSF1 (colony stimulating factor 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381109,910,506 - 109,930,992 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371110,453,233 - 110,473,616 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361110,254,980 - 110,273,878 (+)NCBINCBI36hg18NCBI36
Build 341110,165,498 - 110,184,397NCBI
Celera1108,699,836 - 108,719,046 (+)NCBI
Cytogenetic Map1p13.3NCBI
HuRef1108,322,980 - 108,343,084 (+)NCBIHuRef
CHM1_11110,568,036 - 110,588,399 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CSF1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731066
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.