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Gene: CSF1 (colony stimulating factor 1) Homo sapiens
Symbol: CSF1
Name: colony stimulating factor 1
Description: Exhibits cytokine activity; growth factor activity; and protein homodimerization activity. Involved in several processes, including positive regulation of cell differentiation; positive regulation of macromolecule metabolic process; and positive regulation of macrophage chemotaxis. Localizes to several cellular components, including the extracellular space; nuclear body; and perinuclear region of cytoplasm. Implicated in interstitial cystitis. Biomarker of several diseases, including amyloidosis; atherosclerosis; end stage renal failure; glomerulonephritis (multiple); and vesicoureteral reflux.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: colony stimulating factor 1 (macrophage); CSF-1; lanimostim; macrophage colony stimulating factor; macrophage colony stimulating factor 1; macrophage colony-stimulating factor 1; MCSF; MGC31930
Mus musculus (house mouse) : Csf1 (colony stimulating factor 1 (macrophage))  MGI  Alliance
Rattus norvegicus (Norway rat) : Csf1 (colony stimulating factor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Csf1 (colony stimulating factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CSF1 (colony stimulating factor 1)
Canis lupus familiaris (dog) : CSF1 (colony stimulating factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Csf1 (colony stimulating factor 1)
Sus scrofa (pig) : CSF1 (colony stimulating factor 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381109,910,506 - 109,930,992 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371110,453,233 - 110,473,616 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361110,254,980 - 110,273,878 (+)NCBINCBI36hg18NCBI36
Build 341110,165,498 - 110,184,397NCBI
Celera1108,699,836 - 108,719,046 (+)NCBI
Cytogenetic Map1p13.3NCBI
HuRef1108,322,980 - 108,343,084 (+)NCBIHuRef
CHM1_11110,568,036 - 110,588,399 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CSF1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731066
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.