Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: AGT (angiotensinogen) Homo sapiens
Analyze
Symbol: AGT
Name: angiotensinogen
CRRD ID: 731070
Description: Exhibits angiotensin receptor binding activity and molecular function regulator. Involved in several processes, including positive regulation of branching involved in ureteric bud morphogenesis; positive regulation of cellular metabolic process; and regulation of signal transduction. Localizes to extracellular space. Implicated in several diseases, including Fabry disease; Henoch-Schoenlein purpura; artery disease (multiple); heart conduction disease (multiple); and hydronephrosis. Biomarker of several diseases, including alcoholic hepatitis; chronic myeloid leukemia; intermediate coronary syndrome; neurodegenerative disease (multiple); and systemic scleroderma (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: alpha-1 antiproteinase, antitrypsin; angiotensin I; angiotensin II; angiotensinogen (serine (or cysteine) proteinase inhibitor, clade a (alpha-1 antiproteinase, antitrypsin), member 8); angiotensinogen (serpin peptidase inhibitor, clade A, member 8); ANHU; fetal-liver predominant transporter 1; FLJ92595; FLJ97926; hFLT1; pre-angiotensinogen; serine (or cysteine) proteinase inhibitor; serpin A8; serpin peptidase inhibitor, clade A, member 8; SERPINA8
Orthologs:
Mus musculus (house mouse) : Agt (angiotensinogen (serpin peptidase inhibitor, clade A, member 8))  MGI  Alliance
Rattus norvegicus (Norway rat) : Agt (angiotensinogen)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Agt (angiotensinogen)
Pan paniscus (bonobo/pygmy chimpanzee) : AGT (angiotensinogen)
Canis lupus familiaris (dog) : AGT (angiotensinogen)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Agt (angiotensinogen)
Sus scrofa (pig) : AGT (angiotensinogen)
Chlorocebus sabaeus (African green monkey) : AGT (angiotensinogen)
Heterocephalus glaber (naked mole-rat) : Agt (angiotensinogen)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Note: This gene has been reviewed for its involvement in coronavirus biology, and is relevant for disease process.
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1230,702,523 - 230,714,122 (-)EnsemblGRCh38hg38GRCh38
GRCh381230,702,523 - 230,745,583 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371230,838,269 - 230,850,336 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361228,904,892 - 228,916,564 (-)NCBINCBI36hg18NCBI36
Build 341227,145,019 - 227,156,602NCBI
Celera1204,104,291 - 204,116,358 (-)NCBI
Cytogenetic Map1q42.2NCBI
HuRef1201,323,209 - 201,335,277 (-)NCBIHuRef
CHM1_11232,111,282 - 232,123,349 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences