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Gene: PPIA (peptidylprolyl isomerase A) Homo sapiens
Symbol: PPIA
Name: peptidylprolyl isomerase A
Description: Exhibits cyclosporin A binding activity and peptidyl-prolyl cis-trans isomerase activity. Involved in several processes, including lipid droplet organization; positive regulation of viral genome replication; and protein peptidyl-prolyl isomerization. Localizes to the protein-containing complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cyclophilin; cyclophilin A; cyclosporin A-binding protein; CYPA; CYPH; epididymis secretory sperm binding protein Li 69p; HEL-S-69p; MGC117158; MGC12404; MGC23397; peptidyl-prolyl cis-trans isomerase A; peptidylprolyl isomerase A (cyclophilin A); PPIase A; rotamase A; T cell cyclophilin
Mus musculus (house mouse) : Ppia (peptidylprolyl isomerase A)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ppia (peptidylprolyl isomerase A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ppia (peptidylprolyl isomerase A)
Pan paniscus (bonobo/pygmy chimpanzee) : PPIA (peptidylprolyl isomerase A)
Canis lupus familiaris (dog) : LOC403581 (peptidylprolyl isomerase A (cyclophilin A) pseudogene)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ppia (peptidylprolyl isomerase A)
Sus scrofa (pig) : PPIA (peptidylprolyl isomerase A)
more info ...
Related Pseudogenes: PPIAP1   PPIAP10   PPIAP11   PPIAP13   PPIAP14   PPIAP15   PPIAP16   PPIAP17   PPIAP18   PPIAP19   PPIAP2   PPIAP20   PPIAP21   PPIAP22   PPIAP23   PPIAP24   PPIAP25   PPIAP26   PPIAP27   PPIAP28   PPIAP29   PPIAP3   PPIAP30   PPIAP31   PPIAP35   PPIAP36   PPIAP37   PPIAP38   PPIAP39   PPIAP4   PPIAP41   PPIAP42   PPIAP43   PPIAP44   PPIAP45   PPIAP46   PPIAP47   PPIAP48   PPIAP49   PPIAP5   PPIAP50   PPIAP51   PPIAP52   PPIAP53   PPIAP54   PPIAP55   PPIAP57   PPIAP58   PPIAP6   PPIAP63   PPIAP65   PPIAP66   PPIAP67   PPIAP68   PPIAP69   PPIAP7   PPIAP70   PPIAP72   PPIAP73   PPIAP74   PPIAP75   PPIAP76   PPIAP77   PPIAP78   PPIAP79   PPIAP8   PPIAP80   PPIAP82   PPIAP83   PPIAP84   PPIAP85   PPIAP86   PPIAP87   PPIAP88   PPIAP89   PPIAP9   PPIAP90   PPIAP91  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl744,796,680 - 44,824,564 (+)Ensembl
GRCh38744,795,960 - 44,803,117 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37744,836,241 - 44,842,716 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36744,802,766 - 44,809,241 (+)NCBINCBI36hg18NCBI36
Build 34744,609,504 - 44,615,343NCBI
Celera744,935,095 - 44,941,571 (+)NCBI
Cytogenetic Map7p13NCBI
HuRef744,721,292 - 44,727,768 (+)NCBIHuRef
CHM1_1744,840,580 - 44,847,075 (+)NCBICHM1_1
CRA_TCAGchr7v2744,875,748 - 44,882,224 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PPIA
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731273
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-01-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.