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Gene: MAX (MYC associated factor X) Homo sapiens
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Symbol: MAX
Name: MYC associated factor X
Description: Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific; E-box binding activity; and protein homodimerization activity. Contributes to RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Localizes to the nucleus and protein-DNA complex. Implicated in lung small cell carcinoma and pheochromocytoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: bHLHd4; bHLHd5; bHLHd6; bHLHd7; bHLHd8; class D basic helix-loop-helix protein 4; helix-loop-helix zipper protein; MGC10775; MGC11225; MGC18164; MGC34679; MGC36767; myc-associated factor X; orf1
Orthologs:
Mus musculus (house mouse) : Max (Max protein)  MGI  Alliance
Rattus norvegicus (Norway rat) : Max (MYC associated factor X)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Max (MYC associated factor X)
Pan paniscus (bonobo/pygmy chimpanzee) : MAX (MYC associated factor X)
Canis lupus familiaris (dog) : MAX (MYC associated factor X)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Max (MYC associated factor X)
Sus scrofa (pig) : MAX (MYC associated factor X)
Chlorocebus sabaeus (African green monkey) : MAX (MYC associated factor X)
Heterocephalus glaber (naked mole-rat) : Max (MYC associated factor X)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1465,006,174 - 65,102,695 (-)EnsemblGRCh38hg38GRCh38
GRCh381465,006,101 - 65,102,695 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371465,472,819 - 65,569,413 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361464,542,645 - 64,638,980 (-)NCBINCBI36hg18NCBI36
Build 341464,542,644 - 64,638,980NCBI
Celera1445,527,481 - 45,623,823 (-)NCBI
Cytogenetic Map14q23.3NCBI
HuRef1445,642,154 - 45,738,669 (-)NCBIHuRef
CHM1_11465,411,018 - 65,507,560 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on MAX
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731306
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.