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Gene: USP2 (ubiquitin specific peptidase 2) Homo sapiens
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Symbol: USP2
Name: ubiquitin specific peptidase 2
Description: Exhibits cyclin binding activity; thiol-dependent ubiquitin-specific protease activity; and ubiquitin protein ligase binding activity. Involved in several processes, including negative regulation of transcription by RNA polymerase II; protein deubiquitination; and protein stabilization. Predicted to localize to the cytoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 41 kDa ubiquitin-specific protease; deubiquitinating enzyme 2; ubiquitin carboxyl-terminal hydrolase 2; ubiquitin specific protease 12; ubiquitin specific protease 2; ubiquitin specific protease 9; ubiquitin thioesterase 2; ubiquitin thiolesterase 2; ubiquitin-specific-processing protease 2; UBP41; USP9
Orthologs:
Mus musculus (house mouse) : Usp2 (ubiquitin specific peptidase 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Usp2 (ubiquitin specific peptidase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Usp2 (ubiquitin specific peptidase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : USP2 (ubiquitin specific peptidase 2)
Canis lupus familiaris (dog) : USP2 (ubiquitin specific peptidase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Usp2 (ubiquitin specific peptidase 2)
Sus scrofa (pig) : USP2 (ubiquitin specific peptidase 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811119,355,215 - 119,381,690 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711119,225,925 - 119,252,436 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611118,732,163 - 118,757,575 (-)NCBINCBI36hg18NCBI36
Build 3411118,732,754 - 118,740,102NCBI
Celera11116,386,596 - 116,413,112 (-)NCBI
Cytogenetic Map11q23.3NCBI
HuRef11115,167,582 - 115,194,094 (-)NCBIHuRef
CHM1_111119,112,501 - 119,139,031 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on USP2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731337
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.