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Gene: Akap1 (A kinase (PRKA) anchor protein 1) Mus musculus
Symbol: Akap1
Name: A kinase (PRKA) anchor protein 1
Description: Predicted to have several functions, including enzyme binding activity; protein kinase A regulatory subunit binding activity; and tubulin binding activity. Predicted to be involved in negative regulation of cardiac muscle hypertrophy; negative regulation of protein dephosphorylation; and negative regulation of protein import into nucleus. Localizes to mitochondrion. Is expressed in several structures, including brown fat; central nervous system; genitourinary system; gut; and olfactory epithelium. Orthologous to human AKAP1 (A-kinase anchoring protein 1); PARTICIPATES IN protein kinase A (PKA) signaling pathway; vascular endothelial growth factor signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: a kinase anchor protein 1, mitochondrial; A-kinase anchor protein 1, mitochondrial; Akap; AKAP121; AKAP84; C76494; C81186; D-AKAP-1; DAKAP1; dual specificity A-kinase-anchoring protein 1; PRKA1; protein kinase A-anchoring protein 1; S-AKAP; S-AKAP84; spermatid A-kinase anchor protein
Homo sapiens (human) : AKAP1 (A-kinase anchoring protein 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Akap1 (A-kinase anchoring protein 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Akap1 (A-kinase anchoring protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : AKAP1 (A-kinase anchoring protein 1)
Canis lupus familiaris (dog) : AKAP1 (A-kinase anchoring protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Akap1 (A-kinase anchoring protein 1)
Sus scrofa (pig) : AKAP1 (A-kinase anchoring protein 1)
Chlorocebus sabaeus (African green monkey) : AKAP1 (A-kinase anchoring protein 1)
Heterocephalus glaber (naked mole-rat) : Akap1 (A-kinase anchoring protein 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1188,830,792 - 88,864,586 (-)EnsemblGRCm38mm10GRCm38
GRCm381188,830,792 - 88,864,596 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371188,692,106 - 88,725,900 (-)NCBIGRCm37mm9NCBIm37
MGSCv361188,647,760 - 88,667,593 (-)NCBImm8
Celera1198,443,444 - 98,477,088 (-)NCBICelera
Cytogenetic Map11CNCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Akap1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731357
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.