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Gene: Bdkrb1 (bradykinin receptor, beta 1) Mus musculus
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Symbol: Bdkrb1
Name: bradykinin receptor, beta 1
Description: Exhibits peptide binding activity. Involved in response to lipopolysaccharide. Predicted to localize to the neuron projection and plasma membrane. Human ortholog(s) of this gene implicated in diabetic retinopathy; end stage renal failure; hypertension; and pulmonary fibrosis. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and liver and biliary system. Orthologous to human BDKRB1 (bradykinin receptor B1); PARTICIPATES IN G protein mediated signaling pathway via Galphai family; G protein mediated signaling pathway via Galphaq family; kallikrein-kinin cascade pathway; INTERACTS WITH (+)-pilocarpine; 17beta-estradiol; [des-Arg(9)]-bradykinin.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: B1 bradykinin receptor; B1BKR; B1R; Bdkrb; BK-1 receptor; BKR1; BRADYB1; kinin B1
Orthologs:
Homo sapiens (human) : BDKRB1 (bradykinin receptor B1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Bdkrb1 (bradykinin receptor B1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bdkrb1 (bradykinin receptor B1)
Pan paniscus (bonobo/pygmy chimpanzee) : BDKRB1 (bradykinin receptor B1)
Canis lupus familiaris (dog) : BDKRB1 (bradykinin receptor B1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bdkrb1 (bradykinin receptor B1)
Sus scrofa (pig) : BDKRB1 (bradykinin receptor B1)
Chlorocebus sabaeus (African green monkey) : BDKRB1 (bradykinin receptor B1)
Heterocephalus glaber (naked mole-rat) : Bdkrb1 (bradykinin receptor B1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl12105,603,085 - 105,605,428 (+)Ensembl
GRCm3812105,604,091 - 105,605,511 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3712106,842,301 - 106,843,638 (+)NCBIGRCm37mm9NCBIm37
MGSCv3612106,005,141 - 106,006,478 (+)NCBImm8
Celera12106,838,703 - 106,840,040 (+)NCBICelera
Cytogenetic Map12 ENCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on Bdkrb1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731358
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.