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Gene: TFF2 (trefoil factor 2) Homo sapiens
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Symbol: TFF2
Name: trefoil factor 2
Description: Predicted to have CXCR4 chemokine receptor binding activity. Predicted to be involved in chemokine-mediated signaling pathway; maintenance of gastrointestinal epithelium; and negative regulation of gastric acid secretion. Predicted to localize to the extracellular space. Biomarker of prostate cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: SML1; SP; spasmolysin; spasmolytic polypeptide; spasmolytic protein 1; trefoil factor 2 (spasmolytic protein 1)
Orthologs:
Mus musculus (house mouse) : Tff2 (trefoil factor 2 (spasmolytic protein 1))  MGI  Alliance
Rattus norvegicus (Norway rat) : Tff2 (trefoil factor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tff2 (trefoil factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TFF2 (trefoil factor 2)
Canis lupus familiaris (dog) : TFF2 (trefoil factor 2)
Sus scrofa (pig) : TFF2 (trefoil factor 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382142,346,357 - 42,350,994 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372143,766,466 - 43,771,208 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362142,639,535 - 42,644,176 (-)NCBINCBI36hg18NCBI36
Build 342142,639,537 - 42,644,176NCBI
Celera2128,915,432 - 28,920,174 (-)NCBI
Cytogenetic Map21q22.3NCBI
HuRef2129,183,694 - 29,188,435 (-)NCBIHuRef
CHM1_12143,326,640 - 43,331,381 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on TFF2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731368
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.