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Gene: Tff2 (trefoil factor 2 (spasmolytic protein 1)) Mus musculus
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Symbol: Tff2
Name: trefoil factor 2 (spasmolytic protein 1)
Description: Exhibits CXCR4 chemokine receptor binding activity. Involved in several processes, including negative regulation of gastric acid secretion; negative regulation of macrophage activation; and positive regulation of ERK1 and ERK2 cascade. Localizes to the extracellular space. Is expressed in several structures, including alimentary system; genitourinary system; liver; skeleton; and thymus. Orthologous to human TFF2 (trefoil factor 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: mSP; SP; spasmolytic polypeptide; trefoil factor 2
Orthologs:
Homo sapiens (human) : TFF2 (trefoil factor 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tff2 (trefoil factor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tff2 (trefoil factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TFF2 (trefoil factor 2)
Canis lupus familiaris (dog) : TFF2 (trefoil factor 2)
Sus scrofa (pig) : TFF2 (trefoil factor 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381731,141,062 - 31,144,282 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371731,278,007 - 31,281,227 (-)NCBIGRCm37mm9NCBIm37
MGSCv361730,868,074 - 30,871,294 (-)NCBImm8
Celera1732,058,241 - 32,061,428 (-)NCBICelera
Cytogenetic Map17 A3.3NCBI
cM Map1715.8NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Tff2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731369
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.