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Gene: ATP7B (ATPase copper transporting beta) Homo sapiens
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Symbol: ATP7B
Name: ATPase copper transporting beta
Description: Exhibits ATP binding activity; copper ion binding activity; and copper transmembrane transporter activity, phosphorylative mechanism. Involved in copper ion import; response to copper ion; and sequestering of calcium ion. Localizes to the late endosome and trans-Golgi network membrane. Colocalizes with several cellular components, including the basolateral plasma membrane; perinuclear region of cytoplasm; and trans-Golgi network. Implicated in Wilson disease. Biomarker of breast carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ATPase, Cu(2+)- transporting, beta polypeptide; ATPase, Cu++ transporting, beta polypeptide; copper pump 2; copper-transporting ATPase 2; copper-transporting protein ATP7B; PWD; WC1; WD; Wilson disease-associated protein; WND
Orthologs:
Mus musculus (house mouse) : Atp7b (ATPase, Cu++ transporting, beta polypeptide)  MGI  Alliance
Rattus norvegicus (Norway rat) : Atp7b (ATPase copper transporting beta)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atp7b (ATPase copper transporting beta)
Pan paniscus (bonobo/pygmy chimpanzee) : ATP7B (ATPase copper transporting beta)
Canis lupus familiaris (dog) : ATP7B (ATPase copper transporting beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atp7b (ATPase copper transporting beta)
Sus scrofa (pig) : ATP7B (ATPase copper transporting beta)
more info ...
Related Pseudogenes: ATP7BP1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381351,932,669 - 52,012,130 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371352,506,805 - 52,586,181 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361351,404,806 - 51,483,631 (-)NCBINCBI36hg18NCBI36
Build 341351,404,805 - 51,483,631NCBI
Celera1333,555,444 - 33,634,269 (-)NCBI
Cytogenetic Map13q14.3NCBI
HuRef1333,295,317 - 33,374,147 (-)NCBIHuRef
CHM1_11352,473,433 - 52,553,190 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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