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Gene: Itga6 (integrin alpha 6) Mus musculus
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Symbol: Itga6
Name: integrin alpha 6
Description: Exhibits integrin binding activity. Involved in several processes, including brown fat cell differentiation; cell adhesion mediated by integrin; and filopodium assembly. Localizes to several cellular components, including the basal plasma membrane; external side of plasma membrane; and hemidesmosome. Used to study junctional epidermolysis bullosa Herlitz type. Human ortholog(s) of this gene implicated in junctional epidermolysis bullosa and junctional epidermolysis bullosa with pyloric atresia. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and sensory organ. Orthologous to human ITGA6 (integrin subunit alpha 6).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 5033401O05Rik; AI115430; CD49 antigen-like family member F; Cd49f; integrin alpha-6; VLA-6
Orthologs:
Homo sapiens (human) : ITGA6 (integrin subunit alpha 6)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Itga6 (integrin subunit alpha 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itga6 (integrin subunit alpha 6)
Pan paniscus (bonobo/pygmy chimpanzee) : ITGA6 (integrin subunit alpha 6)
Canis lupus familiaris (dog) : ITGA6 (integrin subunit alpha 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itga6 (integrin subunit alpha 6)
Sus scrofa (pig) : ITGA6 (integrin subunit alpha 6)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl271,745,616 - 71,858,416 (+)Ensembl
GRCm38271,786,886 - 71,858,427 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37271,625,140 - 71,694,815 (+)NCBIGRCm37mm9NCBIm37
MGSCv36271,587,922 - 71,657,597 (+)NCBImm8
Celera273,459,137 - 73,530,691 (+)NCBICelera
Cytogenetic Map2 C2-C3NCBI
cM Map242.79NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Itga6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731430
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-12-10
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.