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Gene: CDK5RAP3 (CDK5 regulatory subunit associated protein 3) Homo sapiens
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Symbol: CDK5RAP3
Name: CDK5 regulatory subunit associated protein 3
CRRD ID: 731437
Description: Exhibits several functions, including MDM2/MDM4 family protein binding activity; NF-kappaB binding activity; and enzyme binding activity. Involved in several processes, including mitotic G2 DNA damage checkpoint; negative regulation of NF-kappaB transcription factor activity; and regulation of cellular protein metabolic process. Localizes to several cellular components, including centrosome; cytosol; and nucleolus. Colocalizes with microtubule.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C53; cdk5 activator-binding protein c53; CDK5 regulatory subunit associated protein IC53-2; CDK5 regulatory subunit-associated protein 3; HSF-27; IC53; ischemic heart CDK5 activator-binding protein C53; LXXLL/leucine-zipper-containing ARFbinding protein; LZAP; MST016; OK/SW-cl.114; PP1553
Orthologs:
Mus musculus (house mouse) : Cdk5rap3 (CDK5 regulatory subunit associated protein 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cdk5rap3 (CDK5 regulatory subunit associated protein 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdk5rap3 (CDK5 regulatory subunit associated protein 3)
Pan paniscus (bonobo/pygmy chimpanzee) : CDK5RAP3 (CDK5 regulatory subunit associated protein 3)
Canis lupus familiaris (dog) : CDK5RAP3 (CDK5 regulatory subunit associated protein 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdk5rap3 (CDK5 regulatory subunit associated protein 3)
Sus scrofa (pig) : CDK5RAP3 (CDK5 regulatory subunit associated protein 3)
Chlorocebus sabaeus (African green monkey) : CDK5RAP3 (CDK5 regulatory subunit associated protein 3)
Heterocephalus glaber (naked mole-rat) : Cdk5rap3 (CDK5 regulatory subunit associated protein 3)
more info ...
Related Pseudogenes: AL121723.1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1747,967,810 - 47,981,781 (+)EnsemblGRCh38hg38GRCh38
GRCh381747,967,904 - 47,981,781 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371746,047,894 - 46,059,152 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361743,403,428 - 43,414,146 (+)NCBINCBI36hg18NCBI36
Build 341743,403,427 - 43,414,146NCBI
Celera1742,501,248 - 42,511,966 (+)NCBI
Cytogenetic Map17q21.32NCBI
HuRef1741,416,597 - 41,427,853 (+)NCBIHuRef
CHM1_11746,112,862 - 46,124,122 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
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miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Clinical Variants

Additional Information

External Database Links
 
More on CDK5RAP3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 731437
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-11-10
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.